BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2023-08-14 (Q2 2023) | Holdings: 107 | Value: $17.3B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seagen Inc.
Reduce 5% $(454.1M)
49.63%
$8.6B
+9.20%
INCY - Incyte Corporation
13.03%
$2.3B
+0.23%
-15.30%
-4.98%
BGNE - BeiGene, Ltd.
12.04%
$2.1B
+20.26%
-3.76%
-6.52%
ACAD - ACADIA Pharmaceuticals Inc.
Add 2% ($22.2M)
5.94%
$1.0B
-23.16%
-19.59%
-45.14%
MDGL - Madrigal Pharmaceuticals, Inc.
2.07%
$356.9M
+60.03%
-6.01%
+42.14%
BMRN - BioMarin Pharmaceutical Inc.
1.91%
$330.3M
-35.62%
-3.48%
-1.13%
IMCR - Immunocore Holdings plc
0.87%
$151.1M
-37.97%
-18.75%
-37.71%
N/A - Invitae Corporation
New Purchase
0.78%
$135.0M
KOD - Kodiak Sciences Inc.
0.69%
$119.4M
+19.30%
-29.12%
-9.12%
AKRO - Akero Therapeutics, Inc.
0.64%
$110.6M
+4.24%
-69.24%
-48.94%
ARGX - argenx SE
0.63%
$109.2M
+13.72%
-3.39%
+4.13%
RYTM - Rhythm Pharmaceuticals, Inc.
0.62%
$107.2M
+130.82%
+20.70%
+75.76%
REPL - Replimune Group, Inc.
0.62%
$106.3M
-54.39%
-43.32%
-47.69%
ABCL - AbCellera Biologics Inc.
Add 57% ($38.8M)
0.62%
$106.3M
-63.93%
-19.11%
-53.21%
KYMR - Kymera Therapeutics, Inc.
Add 52% ($34.4M)
0.58%
$100.6M
+48.35%
-9.46%
+120.42%
ROIV - Roivant Sciences Ltd.
Add 97% ($46.9M)
0.55%
$95.0M
-6.23%
-22.61%
-3.50%
BCRX - BioCryst Pharmaceuticals, Inc.
0.52%
$89.5M
+50.35%
-27.13%
+6.71%
SWTX - SpringWorks Therapeutics, Inc.
Add 9% ($6.5M)
0.46%
$78.7M
+59.37%
-24.70%
+23.54%
TRDA - Entrada Therapeutics, Inc.
0.43%
$73.7M
-50.36%
+6.73%
+6.21%
RVMD - Revolution Medicines, Inc.
0.42%
$72.0M
+30.98%
-29.06%
+44.68%
IMTX - Immatics N.V.
Add 9% ($5.2M)
0.38%
$65.1M
-55.56%
-26.38%
-5.19%
KDNY - Chinook Therapeutics, Inc.
0.32%
$55.9M
MRTX - Mirati Therapeutics, Inc.
0.29%
$50.9M
+39.06%
DICE - DICE Therapeutics, Inc.
0.28%
$48.1M
BMEA - Biomea Fusion, Inc.
0.27%
$46.3M
-92.36%
-50.64%
-69.14%
PRLD - Prelude Therapeutics Inc.
0.26%
$45.6M
-75.86%
-7.63%
+57.22%
DNLI - Denali Therapeutics Inc.
Add 34% ($10.8M)
0.25%
$42.9M
-45.13%
-23.41%
-1.91%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.23%
$39.6M
+60.38%
-7.80%
+53.40%
CERS - Cerus Corporation
0.23%
$39.5M
-33.51%
-9.42%
+14.66%
NRIX - Nurix Therapeutics, Inc.
0.22%
$38.8M
+17.59%
-28.65%
+145.13%
RARE - Ultragenyx Pharmaceutical Inc.
Add 66% ($14.4M)
0.21%
$36.1M
-10.31%
+3.00%
+36.35%
AVTE - Aerovate Therapeutics, Inc.
0.19%
$33.7M
-2.87%
-88.07%
IGMS - IGM Biosciences, Inc.
0.17%
$29.1M
-84.61%
-28.48%
+12.36%
XENE - Xenon Pharmaceuticals Inc.
0.17%
$28.9M
-22.98%
-22.18%
+2.11%
IMGN - ImmunoGen, Inc.
New Purchase
0.17%
$28.7M
+3.44%
DBVT - DBV Technologies S.A.
0.16%
$27.8M
-47.32%
-46.37%
-70.19%
VERV - Verve Therapeutics, Inc.
0.15%
$26.6M
-73.54%
-31.69%
-73.01%
TSVT - 2seventy bio, Inc.
0.15%
$25.3M
-63.88%
-28.84%
IDYA - IDEAYA Biosciences, Inc.
Add 28% ($5.4M)
0.14%
$25.0M
-20.47%
+18.59%
+52.38%
STOK - Stoke Therapeutics, Inc.
Add 1% ($157.6K)
0.13%
$22.6M
+75.05%
-15.41%
+161.47%
BCYC - Bicycle Therapeutics plc
0.12%
$21.5M
-62.57%
-29.92%
+3.46%
GLUE - Monte Rosa Therapeutics, Inc.
New Purchase
0.12%
$20.7M
-36.28%
-43.90%
-25.30%
CABA - Cabaletta Bio, Inc.
Add 19% ($3.2M)
0.12%
$20.6M
-86.08%
+29.34%
-66.79%
KRYS - Krystal Biotech, Inc.
Reduce 44% $(15.6M)
0.12%
$20.0M
+5.36%
-16.72%
+62.26%
SMMT - Summit Therapeutics Inc.
New Purchase
0.09%
$15.8M
+815.33%
-0.50%
+496.48%
ANAB - AnaptysBio, Inc.
0.09%
$15.8M
+15.30%
-25.36%
+68.31%
PRME - Prime Medicine, Inc.
0.09%
$15.1M
-90.29%
-46.34%
-63.87%
PACB - Pacific Biosciences of California, Inc.
0.09%
$15.0M
-91.60%
-31.91%
-85.27%
RLAY - Relay Therapeutics, Inc.
New Purchase
0.08%
$14.6M
-72.43%
-21.42%
-38.69%
SPRY - ARS Pharmaceuticals, Inc.
0.08%
$13.4M
+109.13%
-34.35%
+96.23%
RNA - Avidity Biosciences, Inc.
Reduce 100%
0.00%
$0.00
BPMC - Blueprint Medicines Corporation
Reduce 100%
0.00%
$0.00
FGEN - FibroGen, Inc.
Reduce 100%
0.00%
$0.00
HRTX - Heron Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
NVTA - Invitae Corporation
Reduce 100%
0.00%
$0.00