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Added to YB: 2026-03-17

Pitch date: 2026-03-13

RYTM [neutral]

Rhythm Pharmaceuticals, Inc.

+2.21%

current return

Author Info

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Company Info

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally.

Market Cap

$6.0B

Pitch Price

$88.55

Price Target

N/A

Dividend

N/A

EV/EBITDA

-30.53

P/E

-28.12

EV/Sales

30.68

Sector

Biotechnology

Category

growth

Show full summary:
DD: Rhythm Pharmaceuticals ($RYTM)

RYTM (overview): MC4R agonist setmelanotide for hypothalamic obesity showed 16.4% BMI reduction vs 2.4% placebo increase (p<0.0001) in 142-patient TRANSCEND trial. March 20, 2026 PDUFA key catalyst. Q1 2026 EMANATE data for heterozygous variants critical. $388.9M cash, $16.8M/mo burn = runway to H2 2027. FY25 rev $194.8M (+50% YoY), but net loss $201.9M. rNPV $72/share assumes 95% approval odds for hypothalamic obesity ($42/share), 40% for EMANATE ($22/share). Risks: small trial size, psychiatric AEs, heterozygous non-responders, GLP-1 competition, high SG&A. Neutral.

Read full article (6 min)