BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2019-08-14 (Q2 2019) | Holdings: 103 | Value: $14.7B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seattle Genetics, Inc.
Reduce 2% $(68.7M)
23.55%
$3.5B
+48.81%
+109.86%
INCY - Incyte Corporation
Reduce 7% $(195.0M)
18.46%
$2.7B
-18.43%
+7.09%
+20.41%
BGNE - BeiGene, Ltd.
Reduce 2% $(22.6M)
9.92%
$1.5B
+77.85%
+42.93%
+61.13%
ALXN - Alexion Pharmaceuticals, Inc.
Reduce 4% $(39.3M)
7.35%
$1.1B
+0.49%
-4.72%
ACAD - ACADIA Pharmaceuticals Inc.
Reduce 1% $(11.3M)
7.14%
$1.1B
-23.82%
+57.55%
+34.86%
AMRN - Amarin Corporation plc
Reduce 4% $(32.3M)
5.47%
$805.5M
-96.09%
+60.78%
-53.61%
BMRN - BioMarin Pharmaceutical Inc.
4.42%
$650.0M
-18.43%
+4.54%
+66.47%
GHDX - Genomic Health, Inc.
Reduce 9% $(54.6M)
3.66%
$538.7M
ASND - Ascendis Pharma A/S
2.65%
$390.4M
+42.40%
-2.05%
+29.09%
MRTX - Mirati Therapeutics, Inc.
1.76%
$258.9M
+4.58%
+57.20%
ARGX - argenx SE
0.98%
$144.3M
+336.80%
+4.79%
+79.19%
ARRY1 - Array BioPharma Inc.
Reduce 26% $(46.0M)
0.90%
$132.0M
MDGL - Madrigal Pharmaceuticals, Inc.
0.83%
$122.6M
+197.12%
+9.52%
+22.31%
NBIX - Neurocrine Biosciences, Inc.
Add 29% ($26.7M)
0.81%
$119.5M
+30.02%
+18.86%
+22.67%
HRTX - Heron Therapeutics, Inc.
Add 20% ($18.6M)
0.76%
$111.9M
-88.96%
+24.74%
-8.15%
KOD - Kodiak Sciences, Inc.
0.73%
$107.0M
-65.54%
+181.66%
+368.82%
NVTA - Invitae Corporation
0.62%
$91.7M
-23.18%
+30.57%
TCDA - Tricida, Inc.
Add 9% ($6.6M)
0.53%
$77.7M
+1.94%
-54.58%
ONCE - Spark Therapeutics, Inc.
0.52%
$77.0M
+12.30%
BCEL - Atreca, Inc.
New Purchase
0.45%
$66.6M
-21.26%
+6.79%
GWPH - GW Pharmaceuticals plc
Reduce 13% $(9.9M)
0.43%
$63.9M
-30.41%
-29.47%
INSM - Insmed Incorporated
Add 19% ($9.8M)
0.43%
$63.0M
+340.27%
+29.01%
+76.91%
CERS - Cerus Corporation
0.41%
$60.4M
-76.48%
-14.53%
+35.18%
RYTM - Rhythm Pharmaceuticals, Inc.
0.40%
$59.6M
+210.80%
+9.69%
-7.33%
PRNB - Principia Biopharma Inc.
0.40%
$59.3M
-17.94%
+171.03%
BOLD - Audentes Therapeutics, Inc.
Reduce 12% $(7.9M)
0.39%
$57.0M
ADPT - Adaptive Biotechnologies Corporation
New Purchase
0.38%
$56.3M
-78.84%
-35.19%
-6.71%
BCRX - BioCryst Pharmaceuticals, Inc.
Reduce 5% $(2.8M)
0.37%
$54.5M
+302.96%
-35.19%
+67.78%
RARX - Ra Pharmaceuticals, Inc.
Add 119% ($29.4M)
0.37%
$54.2M
+66.13%
MYOK - MyoKardia, Inc.
0.35%
$51.0M
+1.53%
+89.58%
DBVT - DBV Technologies S.A.
0.31%
$45.3M
-90.15%
-14.09%
-74.05%
KRYS - Krystal Biotech, Inc.
Add 32% ($10.1M)
0.28%
$41.7M
+199.36%
+22.88%
+6.79%
CBAY - CymaBay Therapeutics, Inc.
0.28%
$40.9M
-8.60%
+13.91%
N/A - Neurocrine Biosciences, Inc.
Reduce 42% $(29.6M)
0.28%
$40.5M
QURE - uniQure N.V.
Reduce 14% $(6.8M)
0.27%
$40.5M
-73.21%
-4.94%
-26.02%
KNSA - Kiniksa Pharmaceuticals, Ltd.
Reduce 7% $(2.7M)
0.26%
$37.9M
+152.84%
-39.16%
+62.51%
ZYME - Zymeworks Inc.
0.26%
$37.6M
-52.89%
+50.02%
+24.82%
NLTX - Aquinox Pharmaceuticals, Inc.
0.18%
$25.8M
AXSM - Axsome Therapeutics, Inc.
Reduce 36% $(11.0M)
0.14%
$19.9M
+294.57%
+4.37%
+207.58%
XNCR - Xencor, Inc.
0.12%
$17.5M
-79.89%
-6.45%
-10.92%
MRUS - Merus N.V.
0.12%
$17.0M
+243.70%
-2.48%
-18.93%
N/A - BioMarin Pharmaceutical Inc.
0.11%
$15.6M
ACOR - Acorda Therapeutics, Inc.
New Purchase
0.10%
$15.4M
-28.09%
-74.75%
LJPC - La Jolla Pharmaceutical Company
New Purchase
0.10%
$14.4M
-35.61%
-55.19%
AIMT - Aimmune Therapeutics, Inc.
0.10%
$14.0M
+25.51%
-34.68%
IDRA - Idera Pharmaceuticals, Inc.
Reduce 5% $(625.0K)
0.08%
$12.3M
-5.80%
-11.16%
PTGX - Protagonist Therapeutics, Inc.
New Purchase
0.08%
$12.1M
+380.12%
+7.72%
+66.50%
MRKR - Marker Therapeutics, Inc.
0.08%
$11.9M
-97.35%
-37.28%
-58.33%
AGLE - Aeglea BioTherapeutics, Inc.
0.08%
$11.7M
-92.13%
-0.89%
-12.41%
ASMB - Assembly Biosciences, Inc.
New Purchase
0.07%
$10.8M
-90.53%
+4.08%
+76.94%
ABEO - Abeona Therapeutics Inc.
Reduce 100%
0.00%
$0.00
BLCM - Bellicum Pharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00
CPRX - Catalyst Pharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00
CMTA - Clementia Pharmaceuticals Inc.
Reduce 100%
0.00%
$0.00
DERM2 - Dermira, Inc.
Reduce 100%
0.00%
$0.00
SGMO - Sangamo Therapeutics, Inc.
Reduce 100%
0.00%
$0.00