BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2019-05-15 (Q1 2019) | Holdings: 96 | Value: $15.6B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seattle Genetics, Inc.
23.93%
$3.7B
+22.79%
+146.43%
INCY - Incyte Corporation
18.87%
$2.9B
-14.57%
+9.14%
+26.65%
BGNE - BeiGene, Ltd.
10.11%
$1.6B
+82.30%
+6.72%
+23.41%
ALXN - Alexion Pharmaceuticals, Inc.
7.41%
$1.2B
-13.92%
-20.23%
ACAD - ACADIA Pharmaceuticals Inc.
6.83%
$1.1B
-16.94%
+14.02%
+100.46%
AMRN - Amarin Corporation plc
Add 1% ($12.8M)
5.74%
$897.0M
-96.60%
-11.09%
-55.22%
GHDX - Genomic Health, Inc.
Reduce 13% $(108.2M)
4.57%
$714.4M
+32.88%
BMRN - BioMarin Pharmaceutical Inc.
4.32%
$674.2M
-33.83%
-12.83%
+8.66%
ASND - Ascendis Pharma A/S
Add 19% ($65.1M)
2.55%
$399.0M
+33.14%
-6.43%
+15.09%
MRTX - Mirati Therapeutics, Inc.
1.18%
$184.2M
+29.76%
+49.30%
MDGL - Madrigal Pharmaceuticals, Inc.
0.94%
$146.5M
+157.25%
-13.58%
+13.55%
ARGX - argenx SE
0.81%
$127.3M
+356.34%
+8.36%
+31.09%
BCRX - BioCryst Pharmaceuticals, Inc.
0.79%
$123.1M
+34.21%
-67.67%
-38.45%
HRTX - Heron Therapeutics, Inc.
0.79%
$122.6M
-89.78%
-6.63%
-12.07%
CMTA - Clementia Pharmaceuticals Inc.
0.62%
$97.2M
NBIX - Neurocrine Biosciences, Inc.
Add 50% ($32.4M)
0.62%
$96.8M
+54.98%
+22.50%
+56.73%
ARRY1 - Array BioPharma Inc.
Reduce 24% $(29.2M)
0.60%
$93.7M
NVTA - Invitae Corporation
0.59%
$91.4M
+32.20%
-10.03%
ONCE - Spark Therapeutics, Inc.
Reduce 46% $(72.0M)
0.55%
$85.6M
-7.48%
CBAY - CymaBay Therapeutics, Inc.
Add 16% ($10.5M)
0.49%
$75.8M
-55.54%
-68.68%
RYTM - Rhythm Pharmaceuticals, Inc.
0.48%
$74.2M
+132.31%
-21.97%
-25.00%
GWPH - GW Pharmaceuticals plc
0.46%
$72.2M
-14.27%
-33.17%
N/A - Neurocrine Biosciences, Inc.
0.46%
$72.0M
TCDA - Tricida, Inc.
Add 13% ($7.8M)
0.45%
$69.6M
-4.86%
-13.35%
CERS - Cerus Corporation
0.43%
$67.0M
-76.91%
-0.36%
-0.18%
BOLD - Audentes Therapeutics, Inc.
Add 88% ($31.4M)
0.43%
$66.9M
PRNB - Principia Biopharma Inc.
0.39%
$60.8M
+20.38%
+111.23%
INSM - Insmed Incorporated
Add 12% ($6.6M)
0.39%
$60.4M
+140.45%
-42.76%
-11.55%
KOD - Kodiak Sciences Inc.
0.38%
$59.7M
-56.91%
+39.80%
+640.81%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.35%
$54.2M
+80.47%
-34.10%
+41.69%
MYOK - MyoKardia, Inc.
Add 222% ($36.4M)
0.34%
$52.8M
+12.57%
+129.87%
DBVT - DBV Technologies S.A.
0.27%
$42.5M
-91.29%
-6.36%
-43.90%
QURE - uniQure N.V.
0.23%
$36.1M
-75.32%
-2.95%
+3.41%
NLTX - Aquinox Pharmaceuticals, Inc.
0.19%
$29.5M
ZYME - Zymeworks Inc.
0.18%
$27.6M
-37.81%
+43.58%
+106.69%
KRYS - Krystal Biotech, Inc.
0.17%
$25.8M
+259.78%
+21.85%
+61.53%
RARX - Ra Pharmaceuticals, Inc.
0.12%
$18.4M
+22.07%
MRUS - Merus N.V.
0.11%
$17.1M
+302.22%
+20.66%
-1.00%
AXSM - Axsome Therapeutics, Inc.
New Purchase
0.11%
$17.1M
+353.28%
+6.16%
+267.59%
N/A - BioMarin Pharmaceutical Inc.
0.10%
$15.4M
AIMT - Aimmune Therapeutics, Inc.
0.10%
$15.1M
+5.50%
-17.87%
CPRX - Catalyst Pharmaceuticals, Inc.
New Purchase
0.09%
$14.8M
+595.26%
+60.45%
+26.74%
AGLE - Aeglea BioTherapeutics, Inc.
0.09%
$13.8M
-91.15%
+14.33%
+11.00%
XNCR - Xencor, Inc.
Reduce 3% $(374.8K)
0.09%
$13.3M
-77.09%
+16.64%
-6.30%
IDRA - Idera Pharmaceuticals, Inc.
0.08%
$12.3M
-19.92%
-31.95%
DERM2 - Dermira, Inc.
New Purchase
0.08%
$12.3M
MRKR - Marker Therapeutics, Inc.
0.06%
$9.9M
-97.27%
-3.50%
-59.00%
SGMO - Sangamo Therapeutics, Inc.
0.06%
$9.5M
-95.52%
+9.45%
+0.87%
ABEO - Abeona Therapeutics Inc.
Reduce 39% $(6.0M)
0.06%
$9.5M
-96.59%
-69.90%
-58.82%
BLCM - Bellicum Pharmaceuticals, Inc.
0.06%
$9.0M
-65.26%
-78.18%
CFRX - ContraFect Corporation
Reduce 100%
0.00%
$0.00
NVAX - Novavax, Inc.
Reduce 100%
0.00%
$0.00
SLDB - Solid Biosciences Inc.
Reduce 100%
0.00%
$0.00