BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2018-11-14 (Q3 2018) | Holdings: 97 | Value: $15.2B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seattle Genetics, Inc.
25.93%
$3.9B
+33.61%
+114.49%
INCY - Incyte Corporation
15.59%
$2.4B
+3.57%
+33.95%
+38.01%
BGNE - BeiGene, Ltd.
13.57%
$2.1B
+96.95%
+6.04%
+58.99%
ALXN - Alexion Pharmaceuticals, Inc.
7.83%
$1.2B
+11.83%
-6.36%
GHDX - Genomic Health, Inc.
6.38%
$968.4M
+10.19%
BMRN - BioMarin Pharmaceutical Inc.
4.84%
$735.3M
-36.26%
+3.16%
-17.64%
ACAD - ACADIA Pharmaceuticals Inc.
Add 4% ($25.1M)
3.89%
$590.4M
+23.97%
+33.62%
+164.94%
AMRN - Amarin Corporation plc
Add 50% ($185.5M)
3.65%
$554.3M
-96.61%
+3.21%
+40.39%
MDGL - Madrigal Pharmaceuticals, Inc.
1.65%
$250.4M
+95.21%
-4.07%
-29.44%
ASND - Ascendis Pharma A/S
1.32%
$201.1M
+190.89%
+31.19%
+100.98%
HRTX - Heron Therapeutics, Inc.
1.05%
$159.1M
-93.14%
+0.73%
-21.30%
NVTA - Invitae Corporation
0.93%
$140.5M
+31.75%
+53.57%
DBVT - DBV Technologies S.A.
0.82%
$123.7M
-94.84%
-53.21%
-52.53%
MRTX - Mirati Therapeutics, Inc.
0.78%
$118.4M
+95.32%
+158.10%
NBIX - Neurocrine Biosciences, Inc.
0.77%
$116.1M
+41.40%
-3.08%
+29.94%
BCRX - BioCryst Pharmaceuticals, Inc.
Add 8% ($8.3M)
0.76%
$115.2M
+54.90%
+29.68%
-74.78%
ARRY1 - Array BioPharma Inc.
0.57%
$86.0M
SAGE - Sage Therapeutics, Inc.
Reduce 7% $(6.5M)
0.53%
$80.2M
-93.97%
+50.26%
+36.62%
RYTM - Rhythm Pharmaceuticals, Inc.
0.52%
$79.0M
+137.53%
+16.34%
-15.41%
CERS - Cerus Corporation
0.51%
$77.5M
-74.80%
+28.37%
-11.31%
ARGX - argenx SE
Add 6% ($4.4M)
0.51%
$77.3M
+515.15%
+36.00%
+49.55%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.50%
$76.5M
+61.13%
+4.18%
-61.48%
ONCE - Spark Therapeutics, Inc.
0.50%
$75.5M
+34.65%
+182.75%
GWPH - GW Pharmaceuticals plc
Add 23% ($12.9M)
0.45%
$68.5M
+17.05%
-15.68%
CBAY - CymaBay Therapeutics, Inc.
0.36%
$54.5M
+9.46%
-40.37%
PRNB - Principia Biopharma Inc.
New Purchase
0.34%
$52.2M
+25.73%
+24.69%
TCDA - Tricida, Inc.
0.32%
$48.9M
-25.08%
+9.16%
ECYT - Endocyte, Inc.
Add 12% ($4.8M)
0.30%
$45.3M
IDRA - Idera Pharmaceuticals, Inc.
Reduce 87% $(301.3M)
0.28%
$43.1M
-62.78%
-70.37%
N/A - Corsicanto II Designated Activity Company
New Purchase
0.27%
$41.7M
INSM - Insmed Incorporated
Add 165% ($23.3M)
0.25%
$37.4M
+321.58%
+63.66%
+22.61%
NLTX - Aquinox Pharmaceuticals, Inc.
0.21%
$32.0M
ABEO - Abeona Therapeutics Inc.
0.18%
$28.0M
-96.59%
-9.43%
-68.31%
SLDB - Solid Biosciences Inc.
0.18%
$27.7M
-99.29%
-73.51%
-88.35%
GLPG - Galapagos NV
Reduce 9% $(2.6M)
0.18%
$26.7M
-71.73%
+1.36%
+80.61%
XNCR - Xencor, Inc.
Reduce 31% $(10.5M)
0.15%
$23.5M
-78.37%
-1.41%
-2.70%
MYOK - MyoKardia, Inc.
Reduce 18% $(4.9M)
0.15%
$23.3M
-21.77%
+0.70%
MRUS - Merus N.V.
0.15%
$22.9M
+310.77%
-16.78%
+15.09%
QURE - uniQure N.V.
0.15%
$22.0M
-51.15%
+26.47%
+78.49%
SGMO - Sangamo Therapeutics, Inc.
0.14%
$21.8M
-95.11%
-7.47%
-0.95%
CMTA - Clementia Pharmaceuticals Inc.
Add 62% ($8.3M)
0.14%
$21.6M
-1.87%
ZYME - Zymeworks Inc.
0.14%
$20.6M
-9.07%
+24.98%
+187.51%
AIMT - Aimmune Therapeutics, Inc.
0.12%
$18.4M
-15.41%
-6.81%
N/A - Neurocrine Biosciences, Inc.
New Purchase
0.11%
$17.1M
BLCM - Bellicum Pharmaceuticals, Inc.
Reduce 35% $(8.7M)
0.11%
$16.5M
-26.79%
-79.61%
N/A - BioMarin Pharmaceutical Inc.
New Purchase
0.10%
$15.8M
BOLD - Audentes Therapeutics, Inc.
0.10%
$15.6M
CFRX - ContraFect Corporation
0.10%
$14.8M
-78.00%
-85.44%
AGLE - Aeglea BioTherapeutics, Inc.
New Purchase
0.09%
$13.3M
-92.15%
+7.19%
+0.51%
N/A - BioMarin Pharmaceutical Inc.
New Purchase
0.08%
$12.6M
N/A - BioMarin Pharmaceutical Inc.
Reduce 100%
0.00%
$0.00
BLUE - bluebird bio, Inc.
Reduce 100%
0.00%
$0.00
PHXM - ERYTECH Pharma S.A.
Reduce 100%
0.00%
$0.00
HALO - Halozyme Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
+216.27%
+11.81%
+24.08%
NTLA - Intellia Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
-7.96%
-17.56%
-21.63%
N/A - Novavax, Inc.
Reduce 100%
0.00%
$0.00