BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2024-08-14 (Q2 2024) | Holdings: 95 | Value: $7.8B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
INCY - Incyte Corporation
Reduce 15% $(329.8M)
23.81%
$1.9B
+5.29%
+22.79%
BGNE - BeiGene, Ltd.
19.27%
$1.5B
+29.25%
-0.41%
ACAD - ACADIA Pharmaceuticals Inc.
8.90%
$696.8M
+39.52%
+8.47%
MDGL - Madrigal Pharmaceuticals, Inc.
7.07%
$553.2M
+10.88%
+16.24%
RVMD - Revolution Medicines, Inc.
3.75%
$293.8M
-9.59%
+26.50%
RYTM - Rhythm Pharmaceuticals, Inc.
3.36%
$262.7M
+30.85%
+19.97%
INSM - Insmed Incorporated
Add 943% ($216.6M)
3.06%
$239.6M
-7.53%
-12.09%
BCYC - Bicycle Therapeutics plc
Add 90% ($90.2M)
2.43%
$190.3M
-63.53%
-3.33%
SMMT - Summit Therapeutics Inc.
New Purchase
2.31%
$181.1M
+59.08%
+59.91%
KYMR - Kymera Therapeutics, Inc.
2.29%
$179.0M
-32.56%
-4.53%
EWTX - Edgewise Therapeutics, Inc.
1.34%
$105.2M
-18.54%
+79.35%
ALKS - Alkermes plc
New Purchase
1.29%
$100.8M
+14.13%
+5.11%
N/A - Insmed Incorporated
New Purchase
1.16%
$90.4M
REPL - Replimune Group, Inc.
Add 5% ($4.5M)
1.16%
$90.4M
-10.20%
+8.00%
DNLI - Denali Therapeutics Inc.
1.11%
$86.6M
-42.76%
+8.30%
ABCL - AbCellera Biologics Inc.
1.04%
$81.5M
-24.06%
-0.38%
NRIX - Nurix Therapeutics, Inc.
1.04%
$81.0M
-52.61%
+2.18%
IMTX - Immatics N.V.
0.96%
$74.9M
-54.90%
-31.63%
TRDA - Entrada Therapeutics, Inc.
0.89%
$69.3M
-53.23%
+9.85%
RARE - Ultragenyx Pharmaceutical Inc.
0.77%
$60.3M
-35.19%
-14.78%
STOK - Stoke Therapeutics, Inc.
Add 30% ($13.5M)
0.75%
$59.0M
-33.98%
-16.75%
N/A - Insmed Incorporated
New Purchase
0.72%
$56.2M
KNSA - Kiniksa Pharmaceuticals International, plc
New Purchase
0.67%
$52.6M
+5.27%
-18.08%
IMCR - Immunocore Holdings plc
0.66%
$51.4M
-1.74%
-15.19%
ARGX - argenx SE
Reduce 26% $(16.9M)
0.61%
$48.1M
+8.73%
+7.01%
KOD - Kodiak Sciences Inc.
0.52%
$40.7M
+25.93%
+104.81%
XENE - Xenon Pharmaceuticals Inc.
0.50%
$38.7M
-26.38%
+1.63%
PRLD - Prelude Therapeutics Inc.
0.49%
$38.6M
-83.32%
-80.41%
IDYA - IDEAYA Biosciences, Inc.
0.48%
$37.3M
-47.60%
-29.82%
CERS - Cerus Corporation
0.44%
$34.3M
-40.65%
-19.63%
SERA - Sera Prognostics, Inc.
0.41%
$32.2M
-77.29%
-10.63%
KRYS - Krystal Biotech, Inc.
0.40%
$31.2M
-34.43%
-11.11%
CELC - Celcuity Inc.
Add 21% ($5.3M)
0.39%
$30.7M
-38.45%
-26.69%
ROIV - Roivant Sciences Ltd.
Reduce 62% $(48.8M)
0.38%
$29.6M
-4.43%
-2.61%
IGMS - IGM Biosciences, Inc.
0.36%
$28.1M
-86.52%
+0.53%
CERE - Cerevel Therapeutics Holdings, Inc.
Reduce 57% $(37.5M)
0.36%
$28.0M
AKRO - Akero Therapeutics, Inc.
Reduce 60% $(37.9M)
0.33%
$25.7M
+102.74%
+14.70%
DYN - Dyne Therapeutics, Inc.
New Purchase
0.30%
$23.7M
-73.43%
-36.93%
ALMS - Alumis Inc.
New Purchase
0.27%
$20.8M
-72.74%
-31.07%
GLUE - Monte Rosa Therapeutics, Inc.
0.23%
$18.4M
-10.49%
+65.74%
MRUS - Merus N.V.
New Purchase
0.23%
$17.8M
+9.40%
-9.11%
NGNE - Neurogene Inc.
0.21%
$16.6M
-50.47%
+0.51%
TCRX - TScan Therapeutics, Inc.
0.21%
$16.3M
-75.47%
-24.36%
SANA - Sana Biotechnology, Inc.
0.17%
$13.0M
-55.98%
-50.91%
IMVT - Immunovant, Inc.
Add 9% ($1.0M)
0.16%
$12.3M
-51.60%
-13.20%
XNCR - Xencor, Inc.
0.13%
$10.3M
-50.37%
+43.11%
NMRA - Neumora Therapeutics, Inc.
New Purchase
0.13%
$10.2M
-93.73%
-5.16%
FATE - Fate Therapeutics, Inc.
Add 65% ($3.9M)
0.13%
$9.8M
-64.72%
-41.11%
TSVT - 2seventy bio, Inc.
0.12%
$9.6M
-22.30%
BMEA - Biomea Fusion, Inc.
0.12%
$9.5M
-74.19%
+17.03%
ADAP - Adaptimmune Therapeutics plc
Reduce 100%
0.00%
$0.00
AVTE - Aerovate Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
BCRX - BioCryst Pharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00
CLDX - Celldex Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
DBVT - DBV Technologies S.A.
Reduce 100%
0.00%
$0.00
RLAY - Relay Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
TSHA - Taysha Gene Therapies, Inc.
Reduce 100%
0.00%
$0.00
VERV - Verve Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
KNSA - Kiniksa Pharmaceuticals, Ltd.
Reduce 100%
0.00%
$0.00