BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2024-05-15 (Q1 2024) | Holdings: 87 | Value: $8.0B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
INCY - Incyte Corporation
25.86%
$2.1B
+14.42%
+9.32%
+11.34%
BGNE - BeiGene, Ltd.
20.73%
$1.7B
+45.98%
+15.71%
+35.75%
ACAD - ACADIA Pharmaceuticals Inc.
9.94%
$792.6M
+42.94%
+2.05%
+47.51%
MDGL - Madrigal Pharmaceuticals, Inc.
6.60%
$526.0M
+29.91%
+18.37%
+37.32%
RYTM - Rhythm Pharmaceuticals, Inc.
3.48%
$277.2M
+54.83%
+16.33%
+51.30%
RVMD - Revolution Medicines, Inc.
Add 47% ($77.4M)
3.05%
$243.3M
-0.30%
+8.43%
+0.05%
KYMR - Kymera Therapeutics, Inc.
3.02%
$241.0M
-17.53%
+21.87%
-15.83%
ABCL - AbCellera Biologics Inc.
Add 20% ($20.9M)
1.56%
$124.7M
-45.84%
-30.03%
-45.58%
BCYC - Bicycle Therapeutics plc
Add 176% ($78.5M)
1.54%
$123.1M
-63.24%
+0.27%
-63.77%
EWTX - Edgewise Therapeutics, Inc.
Add 88% ($49.7M)
1.34%
$106.5M
-19.14%
+4.47%
-16.31%
IMCR - Immunocore Holdings plc
Reduce 40% $(65.4M)
1.24%
$98.5M
-34.20%
-34.56%
-45.40%
KOD - Kodiak Sciences Inc.
1.14%
$91.1M
-9.81%
-34.48%
-7.16%
ROIV - Roivant Sciences Ltd.
Reduce 2% $(1.9M)
0.98%
$78.1M
-4.27%
-2.53%
-6.01%
REPL - Replimune Group, Inc.
0.98%
$78.0M
+35.24%
+52.26%
+18.22%
DNLI - Denali Therapeutics Inc.
Add 43% ($23.1M)
0.96%
$76.6M
-36.22%
+10.89%
-33.62%
TRDA - Entrada Therapeutics, Inc.
0.86%
$68.9M
-48.05%
+12.99%
-44.70%
AKRO - Akero Therapeutics, Inc.
Add 15% ($8.7M)
0.86%
$68.5M
+136.88%
+18.61%
+85.45%
RARE - Ultragenyx Pharmaceutical Inc.
0.86%
$68.5M
-17.66%
+28.36%
-13.84%
IMTX - Immatics N.V.
Add 10% ($6.4M)
0.85%
$67.7M
-51.96%
+2.58%
-57.75%
CERE - Cerevel Therapeutics Holdings, Inc.
0.85%
$67.6M
ARGX - argenx SE
0.75%
$59.5M
+52.50%
+39.66%
+50.47%
NRIX - Nurix Therapeutics, Inc.
0.72%
$57.1M
-33.02%
+40.39%
-39.76%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.70%
$55.4M
+36.25%
+29.48%
+30.73%
BCRX - BioCryst Pharmaceuticals, Inc.
0.65%
$51.4M
+67.97%
+19.38%
+60.00%
AVTE - Aerovate Therapeutics, Inc.
0.62%
$49.7M
-91.62%
SERA - Sera Prognostics, Inc.
0.62%
$49.5M
-81.54%
-17.81%
-72.66%
PRLD - Prelude Therapeutics Inc.
0.60%
$48.0M
-77.05%
+34.97%
-77.12%
IDYA - IDEAYA Biosciences, Inc.
0.58%
$46.6M
-53.13%
-11.03%
-58.01%
STOK - Stoke Therapeutics, Inc.
Add 66% ($18.1M)
0.57%
$45.5M
-32.34%
+3.76%
-30.78%
XENE - Xenon Pharmaceuticals Inc.
0.54%
$42.8M
-28.39%
-5.91%
-24.82%
IGMS - IGM Biosciences, Inc.
Add 11% ($3.8M)
0.49%
$39.5M
-86.63%
-3.68%
-87.58%
CERS - Cerus Corporation
0.46%
$36.8M
-37.13%
+11.39%
-34.16%
GLUE - Monte Rosa Therapeutics, Inc.
0.43%
$34.7M
-20.38%
-10.86%
-24.19%
CELC - Celcuity Inc.
New Purchase
0.42%
$33.5M
-45.40%
-15.00%
-45.51%
BMEA - Biomea Fusion, Inc.
0.40%
$31.5M
-89.12%
-56.34%
-88.52%
KRYS - Krystal Biotech, Inc.
0.38%
$30.2M
-22.87%
+17.81%
-20.03%
SANA - Sana Biotechnology, Inc.
New Purchase
0.30%
$23.8M
-76.77%
-46.57%
-81.32%
NGNE - Neurogene Inc.
Add 1% ($127.2K)
0.29%
$23.2M
-49.36%
+4.26%
-46.44%
VERV - Verve Therapeutics, Inc.
0.28%
$22.5M
-34.27%
-33.97%
-31.61%
TCRX - TScan Therapeutics, Inc.
0.28%
$22.1M
-83.88%
-35.29%
-86.02%
ADAP - Adaptimmune Therapeutics plc
New Purchase
0.21%
$17.0M
-78.17%
-19.40%
-79.26%
IMVT - Immunovant, Inc.
0.17%
$13.7M
-51.80%
-2.47%
-53.07%
TSVT - 2seventy bio, Inc.
0.17%
$13.4M
-1.24%
FATE - Fate Therapeutics, Inc.
New Purchase
0.17%
$13.3M
-71.60%
-20.19%
-74.88%
XNCR - Xencor, Inc.
New Purchase
0.15%
$12.1M
-62.37%
-23.66%
-62.09%
TSHA - Taysha Gene Therapies, Inc.
New Purchase
0.14%
$11.5M
-12.58%
-27.42%
-12.90%
DBVT - DBV Technologies S.A.
0.14%
$10.9M
+26.53%
-29.35%
+68.21%
CLDX - Celldex Therapeutics, Inc.
0.13%
$10.4M
-50.59%
-14.61%
-48.91%
RLAY - Relay Therapeutics, Inc.
0.12%
$9.6M
-55.88%
-5.15%
-58.68%
INSM - Insmed Incorporated
0.12%
$9.3M
+181.51%
+207.63%
+175.01%
DAWN - Day One Biopharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00
GRCL - Gracell Biotechnologies Inc.
Reduce 100%
0.00%
$0.00
N/A - Invitae Corporation
Reduce 100%
0.00%
$0.00
MRTX - Mirati Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
PRME - Prime Medicine, Inc.
Reduce 100%
0.00%
$0.00
SPRY - ARS Pharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00