BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2024-02-14 (Q4 2023) | Holdings: 84 | Value: $8.8B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
INCY - Incyte Corporation
25.85%
$2.3B
+12.00%
-1.79%
+22.69%
BGNE - BeiGene, Ltd.
Reduce 9% $(198.4M)
21.69%
$1.9B
+67.35%
+12.35%
+62.26%
ACAD - ACADIA Pharmaceuticals Inc.
15.27%
$1.3B
-16.10%
-41.19%
-23.22%
MDGL - Madrigal Pharmaceuticals, Inc.
Add 27% ($98.3M)
5.19%
$455.8M
+26.53%
-2.67%
+56.23%
RYTM - Rhythm Pharmaceuticals, Inc.
Reduce 5% $(14.0M)
3.35%
$294.1M
+21.73%
-21.40%
+14.23%
MRTX - Mirati Therapeutics, Inc.
Add 192% ($159.3M)
2.76%
$242.1M
IMCR - Immunocore Holdings plc
1.96%
$172.2M
-49.78%
-23.15%
-59.93%
KYMR - Kymera Therapeutics, Inc.
Add 26% ($31.7M)
1.74%
$152.7M
-18.50%
-1.18%
+2.09%
RVMD - Revolution Medicines, Inc.
Add 91% ($70.5M)
1.68%
$147.7M
+31.33%
+31.30%
+38.23%
N/A - Invitae Corporation
1.49%
$131.2M
ABCL - AbCellera Biologics Inc.
Add 10% ($12.3M)
1.49%
$130.8M
-61.81%
-30.06%
-35.16%
ROIV - Roivant Sciences Ltd.
Reduce 36% $(48.1M)
0.97%
$85.3M
-5.34%
-0.95%
-8.01%
REPL - Replimune Group, Inc.
Add 108% ($41.9M)
0.92%
$80.5M
+26.84%
-3.81%
+98.16%
TRDA - Entrada Therapeutics, Inc.
0.84%
$73.4M
-49.23%
-3.21%
-12.56%
RARE - Ultragenyx Pharmaceutical Inc.
Add 7% ($4.8M)
0.80%
$70.1M
-26.53%
-11.23%
-5.83%
CERE - Cerevel Therapeutics Holdings, Inc.
New Purchase
0.77%
$67.8M
IMTX - Immatics N.V.
Add 4% ($2.1M)
0.70%
$61.5M
-51.88%
-1.07%
-56.79%
BCRX - BioCryst Pharmaceuticals, Inc.
Reduce 20% $(15.5M)
0.69%
$60.7M
+90.94%
+12.97%
+66.25%
ARGX - argenx SE
0.65%
$57.5M
+46.38%
-3.74%
+63.17%
DNLI - Denali Therapeutics Inc.
Add 14% ($6.8M)
0.64%
$56.0M
-27.09%
+14.87%
+19.99%
AKRO - Akero Therapeutics, Inc.
0.63%
$55.3M
+129.33%
-2.68%
+128.36%
KOD - Kodiak Sciences Inc.
0.60%
$52.6M
-31.59%
-24.75%
+3.62%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.56%
$49.3M
+36.80%
+0.50%
-2.25%
XENE - Xenon Pharmaceuticals Inc.
Add 32% ($11.1M)
0.52%
$45.8M
-40.77%
-16.96%
-19.63%
PRLD - Prelude Therapeutics Inc.
0.49%
$43.2M
-74.32%
+15.94%
-72.50%
CERS - Cerus Corporation
Add 13% ($4.8M)
0.48%
$42.1M
-46.41%
-14.35%
-21.52%
NRIX - Nurix Therapeutics, Inc.
0.46%
$40.1M
+13.69%
+70.05%
+78.93%
AVTE - Aerovate Therapeutics, Inc.
Reduce 14% $(6.4M)
0.43%
$38.0M
+7.80%
-87.84%
IDYA - IDEAYA Biosciences, Inc.
0.43%
$37.8M
-57.55%
-9.43%
-56.38%
EWTX - Edgewise Therapeutics, Inc.
New Purchase
0.39%
$34.1M
-21.62%
-2.96%
+43.41%
SERA - Sera Prognostics, Inc.
New Purchase
0.37%
$32.5M
-82.63%
-6.12%
-56.46%
BCYC - Bicycle Therapeutics plc
Add 112% ($17.1M)
0.37%
$32.4M
-62.64%
+1.64%
-44.73%
IGMS - IGM Biosciences, Inc.
Add 17% ($4.4M)
0.35%
$30.7M
-91.70%
-37.97%
-90.46%
BMEA - Biomea Fusion, Inc.
0.35%
$30.6M
-91.64%
-23.16%
-79.16%
GLUE - Monte Rosa Therapeutics, Inc.
0.32%
$27.8M
-18.36%
+2.15%
+27.93%
VERV - Verve Therapeutics, Inc.
Add 19% ($3.8M)
0.27%
$23.6M
-65.26%
-51.37%
-33.76%
KRYS - Krystal Biotech, Inc.
0.24%
$21.1M
+13.16%
+46.61%
+40.77%
GRCL - Gracell Biotechnologies Inc.
New Purchase
0.24%
$20.9M
IMVT - Immunovant, Inc.
0.20%
$17.9M
-60.99%
-18.75%
-45.31%
TCRX - TScan Therapeutics, Inc.
New Purchase
0.18%
$16.2M
-75.39%
+53.70%
-65.40%
DAWN - Day One Biopharmaceuticals, Inc.
0.17%
$14.6M
-57.15%
+10.28%
-19.88%
DBVT - DBV Technologies S.A.
0.16%
$13.9M
-1.76%
-32.20%
-49.65%
RLAY - Relay Therapeutics, Inc.
0.15%
$12.8M
-70.12%
-32.32%
-60.96%
SPRY - ARS Pharmaceuticals, Inc.
New Purchase
0.13%
$11.0M
+102.38%
+24.54%
+65.08%
STOK - Stoke Therapeutics, Inc.
New Purchase
0.12%
$10.7M
+80.34%
+167.11%
+83.55%
TSVT - 2seventy bio, Inc.
0.12%
$10.7M
-12.41%
-57.01%
INSM - Insmed Incorporated
0.12%
$10.6M
+151.19%
-10.19%
+193.08%
CLDX - Celldex Therapeutics, Inc.
New Purchase
0.11%
$9.8M
-45.81%
+10.05%
-38.25%
PRME - Prime Medicine, Inc.
0.10%
$9.1M
-81.93%
+3.52%
-54.21%
NGNE - Neurogene Inc.
New Purchase
0.10%
$8.8M
-42.69%
+13.17%
-41.54%
ADAP - Adaptimmune Therapeutics plc
Reduce 100%
0.00%
$0.00
BMRN - BioMarin Pharmaceutical Inc.
Reduce 100%
0.00%
$0.00
CABA - Cabaletta Bio, Inc.
Reduce 100%
0.00%
$0.00
COGT - Cogent Biosciences, Inc.
Reduce 100%
0.00%
$0.00
HRTX - Heron Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
PACB - Pacific Biosciences of California, Inc.
Reduce 100%
0.00%
$0.00
SGEN - Seagen Inc.
Reduce 100%
0.00%
$0.00
SWTX - SpringWorks Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
TNGX - Tango Therapeutics, Inc.
Reduce 100%
0.00%
$0.00