BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2023-05-15 (Q1 2023) | Holdings: 105 | Value: $18.4B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seagen Inc.
51.68%
$9.5B
+1.88%
INCY - Incyte Corporation
14.22%
$2.6B
-1.00%
-1.51%
-13.48%
BGNE - BeiGene, Ltd.
13.68%
$2.5B
+0.60%
-21.21%
-29.94%
ACAD - ACADIA Pharmaceuticals Inc.
4.29%
$789.3M
-1.01%
+34.24%
-31.85%
MDGL - Madrigal Pharmaceuticals, Inc.
2.04%
$374.3M
-1.98%
-37.47%
-22.67%
BMRN - BioMarin Pharmaceutical Inc.
Reduce 50% $(370.5M)
2.02%
$370.5M
-37.97%
-3.86%
-17.78%
IMCR - Immunocore Holdings plc
0.68%
$124.6M
-39.02%
-0.55%
-9.61%
RYTM - Rhythm Pharmaceuticals, Inc.
Add 2% ($2.6M)
0.63%
$115.9M
+271.02%
+54.02%
+136.96%
KOD - Kodiak Sciences Inc.
0.58%
$107.3M
-35.48%
-50.85%
-29.03%
BCRX - BioCryst Pharmaceuticals, Inc.
0.58%
$106.0M
+25.73%
-19.06%
-24.33%
ARGX - argenx SE
0.57%
$104.4M
+45.29%
+27.22%
-4.55%
AKRO - Akero Therapeutics, Inc.
0.49%
$90.6M
+7.98%
+0.91%
-54.92%
KYMR - Kymera Therapeutics, Inc.
0.46%
$85.3M
+1.72%
-33.91%
+22.17%
REPL - Replimune Group, Inc.
0.44%
$80.9M
-50.90%
+2.79%
-63.26%
ABCL - AbCellera Biologics Inc.
0.43%
$78.8M
-65.82%
-6.94%
-36.04%
SWTX - SpringWorks Therapeutics, Inc.
Add 80% ($31.5M)
0.39%
$70.9M
+55.80%
-5.04%
+49.33%
TRDA - Entrada Therapeutics, Inc.
0.38%
$70.6M
-40.63%
+22.81%
+16.80%
BMEA - Biomea Fusion, Inc.
0.36%
$65.4M
-95.74%
-49.94%
-62.18%
RVMD - Revolution Medicines, Inc.
New Purchase
0.32%
$58.3M
+52.06%
+15.40%
+50.48%
PRLD - Prelude Therapeutics Inc.
0.31%
$57.7M
-86.82%
-46.88%
-36.31%
MRTX - Mirati Therapeutics, Inc.
0.29%
$52.4M
-18.47%
FGEN - FibroGen, Inc.
Add 92% ($23.6M)
0.27%
$49.2M
-98.34%
-92.49%
-92.84%
CERS - Cerus Corporation
0.26%
$47.7M
-32.80%
-4.76%
+3.70%
IGMS - IGM Biosciences, Inc.
0.24%
$43.4M
-90.55%
-45.24%
-30.88%
AVTE - Aerovate Therapeutics, Inc.
Reduce 1% $(270.1K)
0.22%
$39.6M
-26.02%
+8.20%
IMTX - Immatics N.V.
0.19%
$35.8M
-45.11%
+15.89%
+10.08%
ROIV - Roivant Sciences Ltd.
New Purchase
0.19%
$35.3M
+19.07%
+17.12%
+23.62%
NRIX - Nurix Therapeutics, Inc.
0.19%
$34.5M
+0.95%
-18.33%
+46.25%
KDNY - Chinook Therapeutics, Inc.
Reduce 43% $(25.0M)
0.18%
$33.7M
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.16%
$30.1M
+94.73%
+16.94%
+43.13%
DICE - DICE Therapeutics, Inc.
Add 20% ($5.0M)
0.16%
$29.7M
XENE - Xenon Pharmaceuticals Inc.
0.15%
$26.9M
-30.77%
-12.48%
-3.19%
TSVT - 2seventy bio, Inc.
Add 21% ($4.4M)
0.14%
$25.5M
-50.22%
-56.52%
DNLI - Denali Therapeutics Inc.
0.14%
$25.1M
-57.81%
-24.98%
-35.50%
DBVT - DBV Technologies S.A.
0.13%
$24.7M
-60.98%
-28.50%
-72.38%
KRYS - Krystal Biotech, Inc.
0.13%
$24.2M
+41.86%
+37.40%
+84.46%
VERV - Verve Therapeutics, Inc.
0.11%
$20.4M
-74.28%
-13.18%
-63.12%
RARE - Ultragenyx Pharmaceutical Inc.
0.10%
$18.9M
-28.91%
-22.46%
-10.99%
BCYC - Bicycle Therapeutics plc
0.10%
$17.9M
-65.02%
-6.09%
-5.62%
STOK - Stoke Therapeutics, Inc.
New Purchase
0.10%
$17.6M
-17.40%
-52.81%
+21.47%
ANAB - AnaptysBio, Inc.
0.09%
$16.9M
+16.57%
+1.31%
+33.56%
RNA - Avidity Biosciences, Inc.
New Purchase
0.08%
$15.4M
+180.36%
-24.07%
+159.91%
BPMC - Blueprint Medicines Corporation
New Purchase
0.08%
$15.0M
+88.03%
-7.98%
+97.85%
SPRY - ARS Pharmaceuticals, Inc.
0.07%
$13.1M
+87.16%
-11.02%
+18.03%
PACB - Pacific Biosciences of California, Inc.
New Purchase
0.07%
$13.1M
-92.23%
-13.70%
-82.35%
PRME - Prime Medicine, Inc.
0.07%
$12.7M
-90.80%
-9.28%
-45.09%
HRTX - Heron Therapeutics, Inc.
0.07%
$12.3M
+40.30%
+21.64%
+140.30%
NVTA - Invitae Corporation
Add 6% ($646.7K)
0.07%
$12.0M
-19.05%
-99.84%
IDYA - IDEAYA Biosciences, Inc.
Reduce 50% $(11.5M)
0.06%
$11.4M
-7.75%
+17.21%
+92.63%
CABA - Cabaletta Bio, Inc.
New Purchase
0.06%
$11.1M
-83.88%
+12.93%
+8.79%
ADAP - Adaptimmune Therapeutics plc
Reduce 100%
0.00%
$0.00
ASND - Ascendis Pharma A/S
Reduce 100%
0.00%
$0.00
BLUE - bluebird bio, Inc.
Reduce 100%
0.00%
$0.00
N/A - Insmed Incorporated
Reduce 100%
0.00%
$0.00
OPT - Opthea Limited
Reduce 100%
0.00%
$0.00
TVTX - Travere Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
HZNP - Horizon Therapeutics Public Ltd Co
Reduce 100%
0.00%
$0.00