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BAKER BROS. ADVISORS LP 13F Holdings
Holdings from the most recent 13F from BAKER BROS. ADVISORS LP
Filed: 2022-11-14 (Q3 2022) | Holdings: 115 | Value: $15.3B | Filing Link
PREMIUM
Author Returns
Returns are calculated from when the filing is published and are weighted by the size of the holding.
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Filing Returns
Returns are calculated from when the filing is published and are weighted by the size of the holding.
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Holding Returns | |||||||
|---|---|---|---|---|---|---|---|
| Stock | Put/Call | Change | Holding Pct | Value | Current Return | 3M Return | 1Y Return |
| SGEN - Seagen Inc. | 42.04% | $6.4B | +6.47% | +58.95% | |||
| INCY - Incyte Corporation | 15.78% | $2.4B | -16.66% | +1.64% | -29.58% | ||
| BGNE - BeiGene, Ltd. | 10.30% | $1.6B | +16.94% | +13.69% | -6.41% | ||
| ACAD - ACADIA Pharmaceuticals Inc. | 4.49% | $685.9M | +32.25% | +16.31% | +38.38% | ||
| BMRN - BioMarin Pharmaceutical Inc. | 4.23% | $646.0M | -31.92% | +26.82% | +2.06% | ||
| ASND - Ascendis Pharma A/S | 3.28% | $501.1M | +44.88% | -0.36% | -17.29% | ||
| GBT - Global Blood Therapeutics, Inc. | 1.66% | $254.2M | |||||
| BCRX - BioCryst Pharmaceuticals, Inc. | 1.05% | $160.2M | -23.21% | -27.43% | -62.79% | ||
| RYTM - Rhythm Pharmaceuticals, Inc. | New Purchase | 0.97% | $148.5M | +129.53% | -1.35% | +20.02% | |
| KOD - Kodiak Sciences Inc. | 0.88% | $134.0M | -56.07% | -4.65% | -73.90% | ||
| IMCR - Immunocore Holdings plc | 0.77% | $118.3M | -42.36% | +1.62% | -24.50% | ||
| ABCL - AbCellera Biologics Inc. | 0.68% | $103.4M | -86.13% | -31.46% | -68.89% | ||
| ARGX - argenx SE | Reduce 75% $(296.3M) | 0.65% | $98.9M | +51.95% | -0.39% | +29.08% | |
| MRTX - Mirati Therapeutics, Inc. | 0.64% | $98.5M | -36.14% | -26.31% | |||
| MDGL - Madrigal Pharmaceuticals, Inc. | 0.64% | $97.4M | +272.02% | +281.48% | +118.52% | ||
| CCXI - ChemoCentryx, Inc. | 0.61% | $92.6M | |||||
| TVTX - Travere Therapeutics, Inc. | 0.53% | $81.3M | -32.62% | -9.74% | -72.32% | ||
| AKRO - Akero Therapeutics, Inc. | New Purchase | 0.53% | $80.6M | +11.22% | +0.81% | -67.18% | |
| TRDA - Entrada Therapeutics, Inc. | 0.50% | $76.7M | -59.89% | -42.80% | -13.77% | ||
| IGMS - IGM Biosciences, Inc. | 0.47% | $71.8M | -95.06% | -6.77% | -77.06% | ||
| REPL - Replimune Group, Inc. | Add 8% ($5.2M) | 0.44% | $67.2M | -57.14% | +17.66% | -46.73% | |
| PRLD - Prelude Therapeutics Inc. | 0.44% | $66.9M | -88.90% | -27.51% | -57.52% | ||
| KYMR - Kymera Therapeutics, Inc. | 0.41% | $62.7M | -1.72% | +9.42% | -40.02% | ||
| HZNP - Horizon Therapeutics Public Ltd Co | Reduce 16% $(11.1M) | 0.39% | $60.0M | +44.03% | |||
| CERS - Cerus Corporation | 0.38% | $57.8M | -68.95% | -26.16% | -57.70% | ||
| NRIX - Nurix Therapeutics, Inc. | 0.33% | $50.6M | -27.54% | -29.45% | -56.03% | ||
| KDNY - Chinook Therapeutics, Inc. | 0.33% | $49.8M | +0.27% | ||||
| VERV - Verve Therapeutics, Inc. | 0.32% | $48.7M | -83.82% | -21.05% | -58.23% | ||
| IMTX - Immatics N.V. | 0.29% | $44.2M | -50.73% | -27.15% | -18.37% | ||
| FMTX - Forma Therapeutics Holdings, Inc. | New Purchase | 0.25% | $37.6M | ||||
| N/A - Insmed Incorporated | 0.24% | $36.3M | |||||
| KNSA - Kiniksa Pharmaceuticals, Ltd. | 0.24% | $35.9M | +72.29% | -15.11% | -0.94% | ||
| HRTX - Heron Therapeutics, Inc. | 0.22% | $34.3M | -46.13% | -24.64% | -75.36% | ||
| AVTE - Aerovate Therapeutics, Inc. | Reduce 4% $(1.5M) | 0.21% | $32.8M | +33.52% | -26.23% | ||
| TSVT - 2seventy bio, Inc. | 0.20% | $30.0M | -25.53% | -86.57% | |||
| KRYS - Krystal Biotech, Inc. | Reduce 48% $(26.9M) | 0.19% | $29.4M | +61.49% | -5.76% | +27.64% | |
| XENE - Xenon Pharmaceuticals Inc. | 0.18% | $27.1M | -17.74% | +10.66% | -16.88% | ||
| CINC - CinCor Pharma, Inc. | New Purchase | 0.17% | $26.5M | +3.57% | |||
| DBVT - DBV Technologies S.A. | 0.17% | $25.9M | -46.82% | -17.20% | -45.86% | ||
| IDYA - IDEAYA Biosciences, Inc. | New Purchase | 0.16% | $24.9M | +14.18% | -0.29% | +70.26% | |
| DSGN - Design Therapeutics, Inc. | 0.16% | $24.0M | -75.59% | -55.04% | -84.82% | ||
| VSTM - Verastem, Inc. | 0.15% | $22.9M | +52.85% | +44.56% | +24.80% | ||
| ALT - Altimmune, Inc. | Reduce 15% $(3.9M) | 0.15% | $22.6M | -50.55% | +9.20% | -77.78% | |
| NVTA - Invitae Corporation | Reduce 15% $(3.6M) | 0.14% | $20.7M | -36.07% | -83.85% | ||
| BMEA - Biomea Fusion, Inc. | 0.13% | $20.6M | -82.65% | +27.59% | +12.17% | ||
| BCYC - Bicycle Therapeutics plc | New Purchase | 0.13% | $19.6M | -71.89% | -15.70% | -47.37% | |
| RARE - Ultragenyx Pharmaceutical Inc. | 0.13% | $19.5M | -6.25% | +21.79% | +7.66% | ||
| TIL - Instil Bio, Inc. | 0.12% | $18.8M | -39.30% | -63.01% | -84.77% | ||
| VERU - Veru Inc. | New Purchase | 0.12% | $18.5M | -91.95% | -30.27% | -83.20% | |
| RLMD - Relmada Therapeutics, Inc. | New Purchase | 0.12% | $18.3M | -88.21% | -41.67% | -52.36% | |
| AMRN - Amarin Corporation plc | Reduce 100% | 0.00% | $0.00 | ||||
| INSM - Insmed Incorporated | Reduce 100% | 0.00% | $0.00 | ||||
| LEGN - Legend Biotech Corporation | Reduce 100% | 0.00% | $0.00 | ||||
| PACB - Pacific Biosciences of California, Inc. | Reduce 100% | 0.00% | $0.00 | ||||
| N/A - Sarepta Therapeutics, Inc. | Reduce 100% | 0.00% | $0.00 | ||||
| ALKS - Alkermes plc | Reduce 100% | 0.00% | $0.00 | ||||
| AFMD - Affimed N.V. | Reduce 100% | 0.00% | $0.00 | ||||
| MRUS - Merus N.V. | Reduce 100% | 0.00% | $0.00 | ||||