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BAKER BROS. ADVISORS LP 13F Holdings
Holdings from the most recent 13F from BAKER BROS. ADVISORS LP
Filed: 2022-08-15 (Q2 2022) | Holdings: 117 | Value: $17.6B | Filing Link
PREMIUM
Author Returns
Returns are calculated from when the filing is published and are weighted by the size of the holding.
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Filing Returns
Returns are calculated from when the filing is published and are weighted by the size of the holding.
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Holding Returns | |||||||
|---|---|---|---|---|---|---|---|
| Stock | Put/Call | Change | Holding Pct | Value | Current Return | 3M Return | 1Y Return |
| SGEN - Seagen Inc. | 47.09% | $8.3B | -23.15% | +12.94% | |||
| INCY - Incyte Corporation | 15.58% | $2.7B | -13.80% | +1.63% | -14.24% | ||
| BGNE - BeiGene, Ltd. | 10.71% | $1.9B | +25.88% | +5.47% | -1.41% | ||
| BMRN - BioMarin Pharmaceutical Inc. | 3.58% | $631.5M | -40.13% | -11.51% | -7.22% | ||
| ACAD - ACADIA Pharmaceuticals Inc. | 3.35% | $590.7M | +29.94% | -8.49% | +76.20% | ||
| ASND - Ascendis Pharma A/S | Add 7% ($28.9M) | 2.56% | $451.1M | +51.25% | +6.68% | -16.50% | |
| ARGX - argenx SE | 2.41% | $424.2M | +49.44% | -4.83% | +30.85% | ||
| BCRX - BioCryst Pharmaceuticals, Inc. | 0.76% | $134.5M | -27.27% | -12.79% | -53.18% | ||
| KOD - Kodiak Sciences Inc. | Add 9% ($10.5M) | 0.75% | $132.3M | -71.62% | -35.89% | -78.38% | |
| GBT - Global Blood Therapeutics, Inc. | Add 13% ($13.3M) | 0.68% | $119.3M | ||||
| ABCL - AbCellera Biologics Inc. | 0.63% | $111.3M | -85.00% | +7.80% | -59.17% | ||
| MDGL - Madrigal Pharmaceuticals, Inc. | 0.61% | $107.3M | +258.13% | -8.67% | +128.48% | ||
| MRTX - Mirati Therapeutics, Inc. | 0.54% | $94.6M | -14.91% | -53.27% | |||
| IMCR - Immunocore Holdings plc | 0.53% | $94.0M | -32.55% | +16.24% | +10.01% | ||
| HZNP - Horizon Therapeutics Public Ltd Co | Add 28% ($19.9M) | 0.52% | $91.6M | +16.47% | +60.24% | ||
| CERS - Cerus Corporation | Add 17% ($12.5M) | 0.48% | $85.0M | -75.05% | -22.40% | -64.64% | |
| TVTX - Travere Therapeutics, Inc. | 0.45% | $80.0M | -47.02% | -25.36% | -48.22% | ||
| REPL - Replimune Group, Inc. | Add 123% ($34.6M) | 0.36% | $62.8M | -56.11% | -6.06% | -8.11% | |
| TRDA - Entrada Therapeutics, Inc. | Add 3% ($2.0M) | 0.34% | $59.3M | -39.63% | +38.52% | +24.86% | |
| IGMS - IGM Biosciences, Inc. | 0.32% | $56.9M | -95.29% | -4.74% | -72.72% | ||
| KYMR - Kymera Therapeutics, Inc. | Add 21% ($9.7M) | 0.32% | $56.7M | -12.02% | -13.36% | -42.83% | |
| KRYS - Krystal Biotech, Inc. | 0.30% | $53.0M | +62.53% | -2.18% | +57.42% | ||
| PRLD - Prelude Therapeutics Inc. | 0.30% | $52.8M | -89.89% | -12.10% | -59.25% | ||
| NRIX - Nurix Therapeutics, Inc. | Add 58% ($18.1M) | 0.28% | $49.2M | -38.27% | -20.27% | -50.06% | |
| LEGN - Legend Biotech Corporation | Reduce 57% $(63.4M) | 0.27% | $47.1M | -37.85% | +10.88% | +45.23% | |
| ALKS - Alkermes plc | 0.25% | $44.7M | +17.75% | -15.29% | +9.73% | ||
| CCXI - ChemoCentryx, Inc. | Add 96% ($21.7M) | 0.25% | $44.4M | ||||
| KDNY - Chinook Therapeutics, Inc. | Add 9% ($3.5M) | 0.25% | $44.3M | +1.51% | |||
| INSM - Insmed Incorporated | 0.24% | $42.5M | +156.36% | -33.71% | -17.17% | ||
| IMTX - Immatics N.V. | 0.22% | $38.5M | -54.01% | -12.03% | -2.90% | ||
| DBVT - DBV Technologies S.A. | 0.21% | $37.3M | -68.96% | -50.93% | -43.12% | ||
| N/A - Sarepta Therapeutics, Inc. | 0.21% | $36.6M | |||||
| N/A - Insmed Incorporated | 0.19% | $33.3M | |||||
| AVTE - Aerovate Therapeutics, Inc. | 0.18% | $32.4M | -19.35% | -38.83% | |||
| AMRN - Amarin Corporation plc | 0.18% | $31.5M | -65.30% | -26.95% | -36.53% | ||
| VSTM - Verastem, Inc. | 0.18% | $31.3M | -55.24% | -71.36% | -42.92% | ||
| RARE - Ultragenyx Pharmaceutical Inc. | Add 6% ($1.6M) | 0.16% | $28.1M | -33.25% | -30.91% | -27.19% | |
| TSVT - 2seventy bio, Inc. | 0.15% | $27.2M | -2.36% | -65.30% | |||
| KNSA - Kiniksa Pharmaceuticals, Ltd. | 0.15% | $27.1M | +119.06% | +26.90% | +31.55% | ||
| BMEA - Biomea Fusion, Inc. | New Purchase | 0.14% | $25.2M | -88.36% | -38.56% | +36.74% | |
| ALT - Altimmune, Inc. | New Purchase | 0.14% | $24.3M | -69.15% | -45.80% | -84.55% | |
| NVTA - Invitae Corporation | 0.14% | $24.1M | -37.07% | -79.56% | |||
| PACB - Pacific Biosciences of California, Inc. | 0.14% | $24.1M | -88.39% | +32.05% | +29.04% | ||
| XENE - Xenon Pharmaceuticals Inc. | 0.13% | $22.9M | -23.27% | -12.07% | -3.01% | ||
| HRTX - Heron Therapeutics, Inc. | 0.13% | $22.7M | -64.93% | -43.10% | -69.59% | ||
| MRUS - Merus N.V. | Reduce 51% $(23.6M) | 0.13% | $22.5M | +119.28% | -27.77% | -19.87% | |
| VERV - Verve Therapeutics, Inc. | 0.12% | $21.6M | -88.26% | -34.59% | -60.37% | ||
| DSGN - Design Therapeutics, Inc. | 0.11% | $20.1M | -85.43% | -48.28% | -91.68% | ||
| AFMD - Affimed N.V. | New Purchase | 0.10% | $18.3M | -99.91% | -25.98% | -84.11% | |
| TIL - Instil Bio, Inc. | 0.10% | $18.0M | -81.41% | -72.83% | -93.24% | ||
| AXSM - Axsome Therapeutics, Inc. | Reduce 100% | 0.00% | $0.00 | +109.20% | +9.58% | +50.20% | |
| NBIX - Neurocrine Biosciences, Inc. | Reduce 100% | 0.00% | $0.00 | ||||
| RYTM - Rhythm Pharmaceuticals, Inc. | Reduce 100% | 0.00% | $0.00 | ||||