BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2022-05-16 (Q1 2022) | Holdings: 118 | Value: $17.4B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seagen Inc.
38.83%
$6.8B
+18.78%
+34.26%
INCY - Incyte Corporation
Add 8% ($201.4M)
16.50%
$2.9B
-13.53%
-1.83%
-14.21%
BGNE - BeiGene, Ltd.
12.65%
$2.2B
+80.27%
+32.00%
+69.57%
ACAD - ACADIA Pharmaceuticals Inc.
5.83%
$1.0B
+26.66%
+0.18%
+33.18%
BMRN - BioMarin Pharmaceutical Inc.
3.38%
$587.5M
-25.18%
+22.20%
+18.88%
ASND - Ascendis Pharma A/S
3.06%
$533.0M
+89.22%
+12.47%
+5.28%
ARGX - argenx SE
2.03%
$353.0M
+80.83%
+20.69%
+30.25%
BCRX - BioCryst Pharmaceuticals, Inc.
1.19%
$206.7M
+23.56%
+63.79%
-2.64%
MDGL - Madrigal Pharmaceuticals, Inc.
0.85%
$147.1M
+305.99%
+9.96%
+309.88%
KOD - Kodiak Sciences Inc.
Add 9% ($9.6M)
0.71%
$123.0M
-41.58%
+99.14%
-3.26%
MRTX - Mirati Therapeutics, Inc.
0.67%
$115.9M
+38.72%
-19.64%
GBT - Global Blood Therapeutics, Inc.
0.66%
$114.8M
+138.18%
ABCL - AbCellera Biologics Inc.
0.59%
$101.9M
-74.75%
+62.63%
-27.00%
KYMR - Kymera Therapeutics, Inc.
0.58%
$100.9M
+73.84%
+68.68%
+74.43%
HZNP - Horizon Therapeutics Public Ltd Co
Add 50% ($31.5M)
0.54%
$94.6M
-32.37%
+10.12%
TVTX - Travere Therapeutics, Inc.
Add 24% ($16.3M)
0.49%
$85.0M
-37.49%
+15.56%
-28.80%
IGMS - IGM Biosciences, Inc.
0.48%
$84.4M
-91.99%
+53.53%
-24.97%
NVTA - Invitae Corporation
0.45%
$78.7M
+10.39%
-69.61%
IMCR - Immunocore Holdings plc
0.43%
$75.4M
+19.33%
+73.62%
+83.40%
CERS - Cerus Corporation
0.43%
$75.3M
-74.65%
-2.59%
-60.28%
LEGN - Legend Biotech Corporation
Reduce 19% $(17.4M)
0.42%
$73.0M
-29.65%
+9.36%
+73.39%
PRLD - Prelude Therapeutics Inc.
0.40%
$69.9M
-81.35%
+70.53%
+32.63%
AMRN - Amarin Corporation plc
0.40%
$69.6M
-61.37%
+8.67%
-12.00%
NBIX - Neurocrine Biosciences, Inc.
0.36%
$63.5M
+43.88%
+22.74%
+11.43%
MRUS - Merus N.V.
0.31%
$53.9M
+239.00%
+45.10%
+29.38%
KRYS - Krystal Biotech, Inc.
0.31%
$53.7M
+114.25%
+25.75%
+50.01%
INSM - Insmed Incorporated
0.29%
$50.7M
+243.67%
+27.01%
-8.53%
PACB - Pacific Biosciences of California, Inc.
0.28%
$49.5M
-83.03%
+33.98%
+124.47%
RYTM - Rhythm Pharmaceuticals, Inc.
Add 7% ($3.0M)
0.27%
$47.5M
+1764.13%
+634.35%
+400.61%
HRTX - Heron Therapeutics, Inc.
0.27%
$46.5M
-48.77%
+39.24%
-65.94%
TRDA - Entrada Therapeutics, Inc.
0.25%
$44.2M
+25.62%
+110.91%
+122.81%
TIL - Instil Bio, Inc.
0.24%
$41.9M
-80.75%
-1.29%
-91.41%
ALKS - Alkermes plc
0.23%
$39.5M
+6.46%
-12.35%
+6.09%
N/A - Insmed Incorporated
0.22%
$38.6M
N/A - Sarepta Therapeutics, Inc.
0.22%
$38.4M
KDNY - Chinook Therapeutics, Inc.
0.22%
$38.2M
+52.72%
+52.01%
VSTM - Verastem, Inc.
Add 26% ($7.8M)
0.22%
$38.1M
-41.98%
+20.37%
-62.87%
AVTE - Aerovate Therapeutics, Inc.
New Purchase
0.22%
$37.9M
+87.39%
+65.76%
IMTX - Immatics N.V.
0.20%
$35.3M
-16.43%
+74.88%
+54.57%
TSVT - 2seventy bio, Inc.
New Purchase
0.20%
$35.2M
+25.97%
-7.44%
NRIX - Nurix Therapeutics, Inc.
0.20%
$34.4M
+5.77%
+53.53%
-0.40%
VERV - Verve Therapeutics, Inc.
0.19%
$32.3M
-68.86%
+152.76%
+19.94%
RARE - Ultragenyx Pharmaceutical Inc.
0.19%
$32.3M
-39.53%
-16.04%
-12.67%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.16%
$27.8M
+222.26%
+41.11%
+60.78%
REPL - Replimune Group, Inc.
New Purchase
0.16%
$27.4M
-40.17%
+36.04%
+29.91%
AXSM - Axsome Therapeutics, Inc.
New Purchase
0.15%
$25.3M
+239.23%
+39.13%
+153.19%
DBVT - DBV Technologies S.A.
New Purchase
0.13%
$23.2M
-34.25%
+101.57%
+53.54%
DSGN - Design Therapeutics, Inc.
0.13%
$23.2M
-69.50%
+90.27%
-44.07%
CCXI - ChemoCentryx, Inc.
Reduce 44% $(17.9M)
0.13%
$23.0M
+158.29%
XENE - Xenon Pharmaceuticals Inc.
New Purchase
0.13%
$23.0M
-5.56%
+19.15%
+35.22%
ADAP - Adaptimmune Therapeutics plc
Reduce 100%
0.00%
$0.00
N/A - Apellis Pharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00
BLUE - bluebird bio, Inc.
Reduce 100%
0.00%
$0.00
FMTX - Forma Therapeutics Holdings, Inc.
Reduce 100%
0.00%
$0.00
TLIS - Talis Biomedical Corporation
Reduce 100%
0.00%
$0.00
-88.78%
-5.73%
-56.30%
ZYME - Zymeworks Inc.
Reduce 100%
0.00%
$0.00