BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2021-11-15 (Q3 2021) | Holdings: 122 | Value: $22.8B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seagen Inc.
35.26%
$8.0B
-29.34%
-27.75%
BGNE - BeiGene, Ltd.
18.60%
$4.2B
-37.40%
-43.87%
-47.55%
INCY - Incyte Corporation
9.67%
$2.2B
-0.49%
+3.75%
+17.33%
KOD - Kodiak Sciences Inc.
Add 4% ($52.2M)
6.19%
$1.4B
-96.71%
-46.40%
-92.57%
ASND - Ascendis Pharma A/S
Add 28% ($159.6M)
3.18%
$723.9M
+6.75%
-22.83%
-24.71%
ACAD - ACADIA Pharmaceuticals Inc.
3.06%
$696.1M
+8.77%
+38.68%
-23.40%
BMRN - BioMarin Pharmaceutical Inc.
2.59%
$589.0M
-29.65%
+12.28%
+3.99%
ARGX - argenx SE
1.48%
$338.1M
+91.69%
+0.43%
+22.08%
PRLD - Prelude Therapeutics Inc.
1.39%
$316.4M
-94.41%
-35.80%
-51.39%
NVTA - Invitae Corporation
Reduce 4% $(10.7M)
1.23%
$280.7M
-50.00%
-85.31%
MRTX - Mirati Therapeutics, Inc.
1.10%
$249.4M
-33.14%
-48.34%
ABCL - AbCellera Biologics Inc.
0.92%
$209.4M
-87.61%
-39.88%
-10.92%
IGMS - IGM Biosciences, Inc.
0.91%
$207.5M
-97.87%
-72.24%
-56.86%
BCRX - BioCryst Pharmaceuticals, Inc.
0.80%
$182.7M
-8.90%
+67.46%
+9.24%
KYMR - Kymera Therapeutics, Inc.
Add 22% ($25.0M)
0.62%
$140.1M
-51.51%
-32.14%
-52.25%
PACB - Pacific Biosciences of California, Inc.
Add 70% ($57.3M)
0.61%
$139.1M
-96.40%
-55.62%
-59.06%
MDGL - Madrigal Pharmaceuticals, Inc.
0.53%
$119.6M
+203.45%
-1.07%
-22.61%
LEGN - Legend Biotech Corporation
Add 42% ($35.4M)
0.52%
$119.5M
-44.90%
-20.82%
-1.69%
AMRN - Amarin Corporation plc
Reduce 17% $(23.4M)
0.49%
$111.5M
-85.63%
-13.98%
-69.76%
IMCR - Immunocore Holdings plc
0.41%
$93.4M
-5.89%
-38.67%
+62.18%
HRTX - Heron Therapeutics, Inc.
0.38%
$86.9M
-82.80%
-22.96%
-72.10%
CERS - Cerus Corporation
0.37%
$83.5M
-82.11%
-21.41%
-44.37%
GBT - Global Blood Therapeutics, Inc.
0.36%
$82.0M
+2.56%
ALLK - Allakos Inc.
0.33%
$74.4M
-92.10%
-90.88%
NRIX - Nurix Therapeutics, Inc.
0.32%
$73.5M
-68.51%
-52.31%
-59.33%
DBVT - DBV Technologies S.A.
0.31%
$71.6M
-73.15%
-52.41%
-57.56%
TIL - Instil Bio, Inc.
0.31%
$69.6M
-93.49%
-38.38%
-90.48%
VERV - Verve Therapeutics, Inc.
0.29%
$66.6M
-90.24%
-33.76%
-45.65%
VSTM - Verastem, Inc.
0.29%
$66.2M
-79.85%
-56.59%
-87.11%
HZNP - Horizon Therapeutics Public Ltd Co
0.29%
$65.6M
-10.37%
-30.58%
NBIX - Neurocrine Biosciences, Inc.
0.29%
$64.9M
+40.02%
-2.26%
+28.24%
INSM - Insmed Incorporated
0.26%
$59.4M
+130.51%
-20.66%
-40.40%
IMTX - Immatics N.V.
Add 3% ($1.8M)
0.25%
$57.5M
-54.51%
-22.87%
-13.00%
N/A - Apellis Pharmaceuticals, Inc.
New Purchase
0.25%
$57.3M
ADAP - Adaptimmune Therapeutics plc
0.22%
$50.8M
-93.21%
-28.07%
-45.48%
RYTM - Rhythm Pharmaceuticals, Inc.
0.22%
$50.5M
+373.96%
-48.76%
+97.91%
ZYME - Zymeworks Inc.
0.22%
$49.6M
-41.02%
-62.07%
-59.65%
TVTX - Travere Therapeutics, Inc.
New Purchase
0.22%
$49.5M
-48.95%
-3.13%
-28.08%
BLUE - bluebird bio, Inc.
New Purchase
0.21%
$47.8M
-97.84%
-43.47%
-37.80%
TLIS - Talis Biomedical Corporation
0.21%
$47.3M
-98.21%
-60.71%
-90.93%
FMTX - Forma Therapeutics Holdings, Inc.
0.21%
$47.0M
-37.86%
MRUS - Merus N.V.
0.20%
$44.8M
+89.81%
-6.06%
-37.47%
N/A - Insmed Incorporated
0.19%
$43.8M
N/A - Sarepta Therapeutics, Inc.
0.19%
$43.2M
RARE - Ultragenyx Pharmaceutical Inc.
0.18%
$40.1M
-57.68%
-11.49%
-56.20%
ALKS - Alkermes plc
New Purchase
0.17%
$37.9M
+33.34%
+14.83%
-4.07%
FLGT - Fulgent Genetics, Inc.
0.16%
$36.1M
-77.74%
-29.28%
-61.37%
AVTE - Aerovate Therapeutics, Inc.
New Purchase
0.15%
$34.7M
-47.82%
+13.12%
ALGS - Aligos Therapeutics, Inc.
New Purchase
0.14%
$32.2M
-98.74%
-84.92%
-94.25%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.14%
$31.9M
+110.46%
-12.62%
+21.92%
APLS - Apellis Pharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00
AXSM - Axsome Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
+156.72%
-17.38%
+34.47%
BCAB - BioAtla, Inc.
Reduce 100%
0.00%
$0.00
KRYS - Krystal Biotech, Inc.
Reduce 100%
0.00%
$0.00
NLTX - Neoleukin Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
ADCT - ADC Therapeutics SA
Reduce 100%
0.00%
$0.00