BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2021-08-16 (Q2 2021) | Holdings: 120 | Value: $22.8B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seagen Inc.
32.79%
$7.5B
+18.49%
+10.09%
BGNE - BeiGene, Ltd.
17.59%
$4.0B
-10.38%
+38.72%
-34.38%
INCY - Incyte Corporation
11.83%
$2.7B
-11.64%
-11.69%
+0.31%
KOD - Kodiak Sciences Inc.
Add 2% ($24.0M)
5.77%
$1.3B
-95.91%
+22.72%
-86.07%
ACAD - ACADIA Pharmaceuticals Inc.
4.49%
$1.0B
+29.71%
+17.14%
+2.59%
BMRN - BioMarin Pharmaceutical Inc.
2.78%
$633.3M
-22.36%
+7.96%
+26.81%
ASND - Ascendis Pharma A/S
2.05%
$465.7M
+40.54%
+33.74%
-16.47%
NVTA - Invitae Corporation
Reduce 35% $(185.5M)
1.52%
$345.7M
-15.73%
-83.07%
ARGX - argenx SE
1.48%
$337.1M
+89.26%
-0.83%
+26.32%
PRLD - Prelude Therapeutics Incorporated
1.27%
$289.8M
-97.21%
-50.60%
-74.46%
IGMS - IGM Biosciences, Inc.
1.15%
$262.6M
-98.21%
-13.38%
-65.70%
ABCL - AbCellera Biologics Inc.
1.01%
$229.9M
-87.88%
-11.04%
-21.91%
MRTX - Mirati Therapeutics, Inc.
1.00%
$227.7M
+1.59%
-41.16%
BCRX - BioCryst Pharmaceuticals, Inc.
0.88%
$201.0M
-27.80%
-19.34%
-4.30%
MDGL - Madrigal Pharmaceuticals, Inc.
0.64%
$146.0M
+234.62%
+5.71%
-9.37%
APLS - Apellis Pharmaceuticals, Inc.
Add 36% ($37.8M)
0.63%
$143.6M
-69.71%
-19.26%
+22.88%
HRTX - Heron Therapeutics, Inc.
Add 36% ($33.2M)
0.55%
$126.2M
-82.11%
+2.47%
-51.38%
AMRN - Amarin Corporation plc
0.51%
$115.9M
-89.07%
-22.08%
-69.25%
GBT - Global Blood Therapeutics, Inc.
0.49%
$112.7M
+24.96%
+153.93%
PACB - Pacific Biosciences of California, Inc.
0.49%
$112.0M
-96.56%
-3.39%
-72.82%
IMCR - Immunocore Holdings plc
0.43%
$98.4M
+25.90%
+35.47%
+83.18%
KYMR - Kymera Therapeutics, Inc.
0.42%
$95.0M
-40.72%
+25.18%
-42.48%
VSTM - Verastem, Inc.
Add 26% ($18.2M)
0.38%
$87.5M
-76.62%
+17.54%
-51.49%
VERV - Verve Therapeutics, Inc.
New Purchase
0.37%
$85.3M
-92.53%
-30.52%
-39.37%
TLIS - Talis Biomedical Corporation
0.37%
$83.5M
-98.68%
-41.53%
-87.03%
CERS - Cerus Corporation
0.36%
$81.0M
-78.29%
+24.62%
-16.58%
DBVT - DBV Technologies S.A.
0.35%
$79.8M
-82.78%
-37.53%
-47.22%
RYTM - Rhythm Pharmaceuticals, Inc.
Add 11% ($7.5M)
0.33%
$75.6M
+391.82%
-3.77%
+93.74%
TIL - Instil Bio, Inc.
0.33%
$75.2M
-91.63%
+33.48%
-57.08%
LEGN - Legend Biotech Corporation
New Purchase
0.30%
$68.3M
-24.35%
+45.62%
+17.59%
NBIX - Neurocrine Biosciences, Inc.
0.29%
$65.9M
+36.84%
-0.33%
+16.73%
NRIX - Nurix Therapeutics, Inc.
0.29%
$65.1M
-63.70%
+15.54%
-47.30%
INSM - Insmed Incorporated
0.27%
$61.4M
+209.09%
+34.53%
+14.23%
ALLK - Allakos Inc.
0.26%
$60.0M
+3.44%
-95.65%
ZYME - Zymeworks Inc.
0.26%
$59.3M
-63.73%
-37.86%
-79.72%
HZNP - Horizon Therapeutics Public Ltd Co
0.25%
$56.1M
+2.19%
-41.63%
FMTX - Forma Therapeutics Holdings, Inc.
0.22%
$50.4M
-13.63%
-48.44%
IMTX - Immatics N.V.
Add 7% ($3.4M)
0.22%
$49.7M
-54.09%
+4.34%
-3.92%
N/A - Insmed Incorporated
New Purchase
0.19%
$44.1M
MRUS - Merus N.V.
0.19%
$42.9M
+204.89%
+55.14%
+30.51%
RARE - Ultragenyx Pharmaceutical Inc.
0.19%
$42.4M
-60.56%
-10.19%
-45.24%
ADAP - Adaptimmune Therapeutics plc
0.18%
$41.9M
-92.59%
+7.09%
-47.09%
KRYS - Krystal Biotech, Inc.
Reduce 20% $(10.4M)
0.18%
$41.3M
+136.77%
-7.73%
+38.97%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.17%
$39.0M
+136.27%
+11.31%
+3.45%
N/A - Sarepta Therapeutics, Inc.
New Purchase
0.17%
$38.5M
FLGT - Fulgent Genetics, Inc.
0.16%
$37.0M
-78.25%
+3.22%
-49.54%
AXSM - Axsome Therapeutics, Inc.
New Purchase
0.16%
$36.4M
+401.48%
+64.76%
+105.67%
NLTX - Neoleukin Therapeutics, Inc.
0.15%
$35.3M
BCAB - BioAtla, Inc.
0.15%
$35.0M
-98.97%
-28.60%
-74.27%
ADCT - ADC Therapeutics SA
New Purchase
0.15%
$34.5M
-88.18%
-4.40%
-66.12%
ACHL - Achilles Therapeutics plc
Reduce 100%
0.00%
$0.00
ALXN - Alexion Pharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00
ALT - Altimmune, Inc.
Reduce 100%
0.00%
$0.00
-25.61%
-6.60%
+49.22%
BCEL - Atreca, Inc.
Reduce 100%
0.00%
$0.00
DSGN - Design Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
PTGX - Protagonist Therapeutics, Inc.
Reduce 100%
0.00%
$0.00