BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2020-11-16 (Q3 2020) | Holdings: 120 | Value: $25.0B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seagen Inc.
New Purchase
36.96%
$9.3B
-10.39%
+3.71%
BGNE - BeiGene, Ltd.
Add 13% ($436.6M)
15.22%
$3.8B
-11.54%
+28.78%
+36.93%
INCY - Incyte Corporation
11.47%
$2.9B
-22.41%
-0.10%
-22.46%
ACAD - ACADIA Pharmaceuticals Inc.
6.91%
$1.7B
-60.18%
-7.57%
-64.04%
ALXN - Alexion Pharmaceuticals, Inc.
4.01%
$1.0B
+22.84%
KOD - Kodiak Sciences Inc.
Add 7% ($46.0M)
2.92%
$731.4M
-96.84%
+28.45%
-5.02%
BMRN - BioMarin Pharmaceutical Inc.
2.31%
$577.4M
-24.81%
+11.10%
+4.54%
ASND - Ascendis Pharma A/S
Add 4% ($23.1M)
2.18%
$546.3M
-0.91%
+2.34%
-5.71%
NVTA - Invitae Corporation
2.05%
$513.7M
+3.28%
-54.34%
MYOK - MyoKardia, Inc.
Reduce 5% $(21.1M)
1.64%
$410.3M
PRLD - Prelude Therapeutics Incorporated
New Purchase
1.22%
$304.9M
-98.13%
+78.05%
-66.93%
ARGX - argenx SE
1.07%
$267.7M
+120.68%
+42.68%
+15.64%
MRTX - Mirati Therapeutics, Inc.
0.94%
$234.1M
-10.05%
-37.58%
IGMS - IGM Biosciences, Inc.
0.93%
$232.1M
-97.67%
+79.36%
+12.84%
EXAS - Exact Sciences Corporation
0.75%
$188.2M
-53.17%
+17.33%
-26.45%
MDGL - Madrigal Pharmaceuticals, Inc.
0.71%
$178.0M
+127.53%
+0.69%
-28.12%
AMRN - Amarin Corporation plc
Reduce 7% $(10.4M)
0.54%
$134.8M
-87.48%
+68.47%
-10.80%
HRTX - Heron Therapeutics, Inc.
0.35%
$88.8M
-89.72%
+1.15%
-41.08%
FMTX - Forma Therapeutics Holdings, Inc.
Reduce 11% $(11.4M)
0.35%
$88.3M
+4.93%
-54.64%
CERS - Cerus Corporation
0.34%
$85.8M
-78.76%
+26.25%
+21.91%
ZYME - Zymeworks Inc.
0.32%
$79.6M
-72.69%
-2.08%
-53.23%
INSM - Insmed Incorporated
Reduce 25% $(24.2M)
0.29%
$73.0M
+91.46%
+17.08%
-16.67%
AXSM - Axsome Therapeutics, Inc.
Reduce 5% $(3.6M)
0.27%
$68.4M
+42.96%
-2.09%
-53.03%
NBIX - Neurocrine Biosciences, Inc.
Reduce 25% $(22.1M)
0.26%
$65.1M
+32.71%
+24.37%
-3.34%
KYMR - Kymera Therapeutics, Inc.
New Purchase
0.25%
$63.3M
-36.38%
+27.09%
+34.34%
NRIX - Nurix Therapeutics, Inc.
New Purchase
0.25%
$62.5M
-66.94%
+23.70%
+5.23%
ALLK - Allakos Inc.
Reduce 5% $(3.0M)
0.23%
$56.9M
+36.87%
-17.04%
ADCT - ADC Therapeutics SA
0.22%
$55.7M
-90.87%
-6.76%
-26.17%
RYTM - Rhythm Pharmaceuticals, Inc.
Reduce 8% $(5.0M)
0.21%
$53.5M
+181.33%
+31.79%
-44.95%
HZNP - Horizon Therapeutics Public Ltd Co
New Purchase
0.21%
$51.8M
+22.64%
+52.05%
GBT - Global Blood Therapeutics, Inc.
New Purchase
0.20%
$50.7M
+16.10%
-22.15%
ADAP - Adaptimmune Therapeutics plc
Reduce 5% $(2.8M)
0.20%
$50.5M
-94.18%
+31.61%
-15.90%
BCEL - Atreca, Inc.
0.20%
$49.4M
+23.96%
-65.35%
CCXI - ChemoCentryx, Inc.
Reduce 5% $(2.5M)
0.20%
$49.3M
+4.55%
-32.97%
NLTX - Neoleukin Therapeutics, Inc.
Add 12% ($5.1M)
0.18%
$45.9M
BCRX - BioCryst Pharmaceuticals, Inc.
Reduce 8% $(3.7M)
0.17%
$43.6M
+144.99%
+142.94%
+173.70%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.17%
$42.9M
+74.27%
+43.44%
-17.90%
N/A - Neurocrine Biosciences, Inc.
0.17%
$42.3M
KRYS - Krystal Biotech, Inc.
Reduce 5% $(1.8M)
0.13%
$33.4M
+201.70%
+80.34%
+17.58%
PACB - Pacific Biosciences of California, Inc.
New Purchase
0.13%
$32.1M
-93.84%
+182.42%
+72.95%
PTGX - Protagonist Therapeutics, Inc.
Reduce 16% $(6.2M)
0.12%
$31.2M
+118.15%
+16.96%
+67.37%
AGLE - Aeglea BioTherapeutics, Inc.
0.12%
$31.1M
-93.68%
-23.99%
-29.89%
ALT - Altimmune, Inc.
Add 5% ($1.3M)
0.12%
$29.1M
-41.99%
+159.72%
+14.96%
APLS - Apellis Pharmaceuticals, Inc.
0.11%
$27.0M
-55.83%
+19.57%
+17.71%
ASMB - Assembly Biosciences, Inc.
0.10%
$25.3M
-78.83%
+9.34%
-55.30%
DBVT - DBV Technologies S.A.
0.10%
$25.3M
-64.92%
+144.12%
+27.31%
MRUS - Merus N.V.
0.10%
$24.4M
+319.37%
+76.06%
+113.39%
AUPH - Aurinia Pharmaceuticals Inc.
Reduce 5% $(1.2M)
0.10%
$23.8M
-41.32%
+19.39%
+118.56%
CBAY - Cymabay Therapeutics, Inc.
New Purchase
0.09%
$23.5M
-31.27%
-49.05%
ALKS - Alkermes plc
Add 9% ($1.9M)
0.09%
$22.5M
+72.92%
+11.01%
+28.68%
ADPT - Adaptive Biotechnologies Corporation
Reduce 100%
0.00%
$0.00
-87.38%
+32.00%
-31.68%
N/A - BioMarin Pharmaceutical Inc.
Reduce 100%
0.00%
$0.00
FREQ - Frequency Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
GWPH - GW Pharmaceuticals plc
Reduce 100%
0.00%
$0.00
NVAX - Novavax, Inc.
Reduce 100%
0.00%
$0.00
PRNB - Principia Biopharma Inc.
Reduce 100%
0.00%
$0.00
SGEN - Seattle Genetics, Inc.
Reduce 100%
0.00%
$0.00
TCDA - Tricida, Inc.
Reduce 100%
0.00%
$0.00