BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2020-08-14 (Q2 2020) | Holdings: 114 | Value: $22.7B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seattle Genetics, Inc.
Reduce 6% $(474.2M)
35.43%
$8.0B
+12.19%
-1.31%
INCY - Incyte Corporation
14.67%
$3.3B
-31.73%
-11.49%
-22.36%
BGNE - BeiGene, Ltd.
9.79%
$2.2B
+15.65%
+31.85%
+32.13%
ACAD - ACADIA Pharmaceuticals Inc.
8.96%
$2.0B
-45.63%
+37.71%
-57.55%
ALXN - Alexion Pharmaceuticals, Inc.
4.34%
$983.3M
+24.14%
BMRN - BioMarin Pharmaceutical Inc.
4.13%
$936.1M
-51.30%
-35.33%
-37.01%
KOD - Kodiak Sciences Inc.
2.76%
$626.4M
-92.89%
+137.42%
+80.22%
ASND - Ascendis Pharma A/S
2.21%
$501.4M
+14.73%
+15.82%
-18.11%
NVTA - Invitae Corporation
Add 30% ($83.3M)
1.58%
$359.0M
+53.14%
-15.68%
MYOK - MyoKardia, Inc.
Add 78% ($134.3M)
1.35%
$305.7M
+125.56%
AMRN - Amarin Corporation plc
1.05%
$238.7M
-91.54%
-31.53%
-22.77%
ARGX - argenx SE
1.01%
$229.6M
+139.89%
+8.17%
+27.96%
IGMS - IGM Biosciences, Inc.
1.01%
$229.5M
-97.55%
+4.23%
+38.70%
MDGL - Madrigal Pharmaceuticals, Inc.
0.75%
$169.8M
+158.80%
+13.70%
-22.05%
MRTX - Mirati Therapeutics, Inc.
0.71%
$161.0M
+64.94%
-0.87%
EXAS - Exact Sciences Corporation
0.71%
$160.5M
-34.33%
+41.74%
+8.59%
NBIX - Neurocrine Biosciences, Inc.
Reduce 27% $(40.7M)
0.49%
$110.7M
+6.22%
-19.74%
-22.14%
PRNB - Principia Biopharma Inc.
Reduce 19% $(22.4M)
0.42%
$94.5M
FMTX - Forma Therapeutics Holdings, Inc.
New Purchase
0.41%
$93.0M
+22.78%
-35.28%
CERS - Cerus Corporation
0.40%
$90.5M
-81.81%
-13.32%
-15.47%
HRTX - Heron Therapeutics, Inc.
0.39%
$88.5M
-87.84%
+18.76%
-31.18%
INSM - Insmed Incorporated
0.37%
$83.3M
+160.97%
+37.31%
-14.33%
AXSM - Axsome Therapeutics, Inc.
Add 13% ($9.9M)
0.37%
$83.1M
+33.11%
-5.96%
-73.14%
ADCT - ADC Therapeutics SA
New Purchase
0.35%
$79.0M
-92.25%
-14.32%
-34.51%
BCEL - Atreca, Inc.
0.33%
$75.2M
+0.73%
-61.45%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.31%
$71.3M
+54.58%
-10.06%
-33.56%
ADAP - Adaptimmune Therapeutics plc
Add 81% ($29.9M)
0.29%
$66.8M
-96.38%
-37.67%
-51.05%
BCRX - BioCryst Pharmaceuticals, Inc.
Add 26% ($13.4M)
0.29%
$65.6M
+149.42%
+3.25%
+254.29%
DBVT - DBV Technologies S.A.
0.28%
$64.2M
-64.47%
+5.96%
+107.66%
ZYME - Zymeworks Inc.
0.27%
$61.6M
-61.18%
+41.34%
+8.70%
RYTM - Rhythm Pharmaceuticals, Inc.
0.27%
$60.2M
+237.72%
+20.54%
-30.01%
NLTX - Neoleukin Therapeutics, Inc.
0.25%
$56.4M
CCXI - ChemoCentryx, Inc.
Add 10% ($5.0M)
0.24%
$54.4M
+13.56%
-74.20%
ALLK - Allakos Inc.
0.23%
$52.9M
+12.80%
-9.80%
N/A - Neurocrine Biosciences, Inc.
0.23%
$51.1M
AGLE - Aeglea BioTherapeutics, Inc.
New Purchase
0.18%
$40.5M
-90.88%
+45.07%
-3.88%
ASMB - Assembly Biosciences, Inc.
0.16%
$36.0M
-94.42%
-73.39%
-83.48%
KRYS - Krystal Biotech, Inc.
Reduce 14% $(5.3M)
0.15%
$33.9M
+194.30%
-3.71%
+26.12%
PTGX - Protagonist Therapeutics, Inc.
Add 14% ($4.1M)
0.15%
$33.8M
+203.91%
+40.59%
+206.34%
MRUS - Merus N.V.
0.14%
$32.8M
+328.02%
+4.20%
+42.75%
APLS - Apellis Pharmaceuticals, Inc.
0.13%
$29.3M
-41.07%
+33.76%
+95.61%
AUPH - Aurinia Pharmaceuticals Inc.
0.12%
$27.7M
-44.12%
-4.78%
+3.06%
ALKS - Alkermes plc
0.11%
$24.2M
+66.36%
-4.60%
+50.21%
GWPH - GW Pharmaceuticals plc
Reduce 50% $(22.8M)
0.10%
$22.7M
+12.97%
ALT - Altimmune, Inc.
New Purchase
0.10%
$22.6M
-77.93%
-61.71%
-52.64%
ADPT - Adaptive Biotechnologies Corporation
Reduce 38% $(13.6M)
0.10%
$22.4M
-75.71%
+19.13%
-21.28%
FREQ - Frequency Therapeutics, Inc.
Reduce 20% $(5.5M)
0.10%
$22.0M
TCDA - Tricida, Inc.
Reduce 70% $(51.6M)
0.10%
$21.6M
-57.35%
-74.18%
NVAX - Novavax, Inc.
New Purchase
0.09%
$20.1M
-95.07%
-39.16%
+53.90%
N/A - BioMarin Pharmaceutical Inc.
0.08%
$18.3M
AIMT - Aimmune Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
RARX - Ra Pharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00
XNCR - Xencor, Inc.
Reduce 100%
0.00%
$0.00
URGN - UroGen Pharma Ltd.
Reduce 100%
0.00%
$0.00
QURE - uniQure N.V.
Reduce 100%
0.00%
$0.00
-85.35%
+7.98%
-29.92%