BAKER BROS. ADVISORS LP 13F Holdings

Holdings from the most recent 13F from BAKER BROS. ADVISORS LP

Filed: 2020-02-14 (Q4 2019) | Holdings: 99 | Value: $18.8B | Filing Link

PREMIUM

Author Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Filing Returns

Returns are calculated from when the filing is published and are weighted by the size of the holding.

Holding Returns
StockPut/Call
Change
Holding Pct
Value
Current Return
3M Return
1Y Return
SGEN - Seattle Genetics, Inc.
30.41%
$5.7B
+37.82%
+36.97%
INCY - Incyte Corporation
14.84%
$2.8B
-17.65%
+21.67%
+3.96%
BGNE - BeiGene, Ltd.
10.38%
$2.0B
+43.10%
-3.12%
+122.67%
ACAD - ACADIA Pharmaceuticals Inc.
9.29%
$1.7B
-53.19%
+10.31%
+6.60%
ALXN - Alexion Pharmaceuticals, Inc.
4.75%
$893.1M
-0.88%
+52.35%
KOD - Kodiak Sciences Inc.
Add 21% ($136.9M)
4.23%
$794.9M
-94.28%
-4.71%
+145.00%
AMRN - Amarin Corporation plc
Reduce 17% $(151.1M)
3.93%
$739.6M
-96.80%
-57.36%
-57.47%
BMRN - BioMarin Pharmaceutical Inc.
3.41%
$641.7M
-34.35%
+5.97%
-3.98%
ASND - Ascendis Pharma A/S
2.51%
$471.7M
+15.33%
-0.92%
+13.77%
EXAS - Exact Sciences Corporation
New Purchase
1.27%
$239.1M
-42.69%
-12.14%
+57.09%
MRTX - Mirati Therapeutics, Inc.
0.90%
$168.4M
+12.02%
+118.83%
ARGX - argenx SE
0.87%
$163.7M
+259.95%
-1.52%
+132.87%
DBVT - DBV Technologies S.A.
Add 165% ($97.4M)
0.83%
$156.4M
-91.05%
-42.87%
-36.66%
NVTA - Invitae Corporation
Add 3% ($4.9M)
0.78%
$146.7M
-39.59%
+79.88%
HRTX - Heron Therapeutics, Inc.
0.75%
$141.4M
-91.11%
-28.51%
-13.43%
NBIX - Neurocrine Biosciences, Inc.
Reduce 11% $(17.3M)
0.72%
$134.8M
+18.22%
+11.95%
+8.02%
MYOK - MyoKardia, Inc.
Add 17% ($18.7M)
0.69%
$129.3M
+72.88%
IGMS - IGM Biosciences, Inc.
0.64%
$120.0M
-97.11%
+34.12%
+123.62%
MDGL - Madrigal Pharmaceuticals, Inc.
0.57%
$106.5M
+205.06%
+31.22%
+33.45%
RARX - Ra Pharmaceuticals, Inc.
Reduce 11% $(11.8M)
0.52%
$98.3M
PRNB - Principia Biopharma Inc.
Add 8% ($7.3M)
0.52%
$97.9M
+0.36%
AXSM - Axsome Therapeutics, Inc.
Add 7% ($5.9M)
0.46%
$85.8M
+16.48%
-3.77%
-17.25%
ZYME - Zymeworks Inc.
0.41%
$77.7M
-76.19%
-21.90%
-12.94%
TCDA - Tricida, Inc.
0.40%
$74.3M
-15.24%
-81.45%
RYTM - Rhythm Pharmaceuticals, Inc.
0.33%
$62.2M
+243.20%
+3.58%
+62.51%
INSM - Insmed Incorporated
Add 10% ($5.1M)
0.31%
$58.4M
+126.76%
-17.20%
+36.20%
KRYS - Krystal Biotech, Inc.
0.30%
$57.3M
+96.69%
-7.56%
+13.66%
BCEL - Atreca, Inc.
0.29%
$54.7M
-10.57%
-10.24%
BOLD - Audentes Therapeutics, Inc.
Reduce 47% $(42.0M)
0.26%
$48.2M
N/A - Neurocrine Biosciences, Inc.
0.25%
$47.1M
CERS - Cerus Corporation
0.24%
$45.4M
-74.50%
+5.22%
+55.62%
NLTX - Neoleukin Therapeutics, Inc.
Reduce 70% $(97.4M)
0.22%
$41.9M
GWPH - GW Pharmaceuticals plc
0.21%
$38.8M
-8.52%
+68.35%
BCRX - BioCryst Pharmaceuticals, Inc.
Reduce 14% $(6.1M)
0.20%
$37.8M
+283.93%
+88.93%
+269.29%
QURE - uniQure N.V.
0.20%
$37.1M
-77.01%
-7.31%
-41.82%
AUPH - Aurinia Pharmaceuticals Inc.
New Purchase
0.18%
$34.5M
-58.23%
-8.58%
-16.62%
ADPT - Adaptive Biotechnologies Corporation
Reduce 4% $(1.5M)
0.18%
$33.4M
-69.33%
+22.55%
+106.86%
ALLK - Allakos Inc.
0.17%
$32.4M
+1.99%
+103.81%
ASMB - Assembly Biosciences, Inc.
New Purchase
0.17%
$31.5M
-94.23%
+2.79%
-69.98%
KNSA - Kiniksa Pharmaceuticals, Ltd.
0.16%
$31.0M
+57.88%
+23.83%
+26.14%
CCXI - ChemoCentryx, Inc.
New Purchase
0.16%
$29.2M
+9.93%
+23.87%
MRUS - Merus N.V.
Add 76% ($12.4M)
0.15%
$28.7M
+203.08%
-21.03%
+32.05%
URGN - UroGen Pharma Ltd.
Add 11% ($2.8M)
0.15%
$27.7M
-84.83%
-11.81%
-3.69%
AIMT - Aimmune Therapeutics, Inc.
0.12%
$22.6M
-41.66%
FREQ - Frequency Therapeutics, Inc.
New Purchase
0.11%
$21.6M
ALKS - Alkermes plc
Add 27% ($3.4M)
0.09%
$16.2M
+76.05%
-13.58%
+12.00%
N/A - BioMarin Pharmaceutical Inc.
0.08%
$15.8M
UROV - Urovant Sciences Ltd.
New Purchase
0.08%
$15.5M
-27.85%
+35.65%
APLS - Apellis Pharmaceuticals, Inc.
New Purchase
0.08%
$15.2M
-59.41%
-25.68%
+7.24%
XNCR - Xencor, Inc.
0.08%
$14.7M
-78.08%
-13.81%
+37.27%
AGLE - Aeglea BioTherapeutics, Inc.
Reduce 100%
0.00%
$0.00
CBAY - CymaBay Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
GHDX - Genomic Health, Inc.
Reduce 100%
0.00%
$0.00
IDRA - Idera Pharmaceuticals, Inc.
Reduce 100%
0.00%
$0.00
LJPC - La Jolla Pharmaceutical Company
Reduce 100%
0.00%
$0.00
PTGX - Protagonist Therapeutics, Inc.
Reduce 100%
0.00%
$0.00
ONCE - Spark Therapeutics, Inc.
Reduce 100%
0.00%
$0.00